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. 2021 Sep 28;13(9):e18353.
doi: 10.7759/cureus.18353. eCollection 2021 Sep.

Correlation Between the Ratio of Oxygen Saturation to Fraction of Inspired Oxygen and the Ratio of Partial Pressure of Oxygen to Fraction of Inspired Oxygen in Detection and Risk Stratification of Pediatric Acute Respiratory Distress Syndrome

Pooja D Lohano  1 , Sadam H Baloch  1 , Murtaza A Gowa  2 , Syed J Raza  3 , Lareb Soomro  4 , Hira Nawaz  1
Affiliations

Correlation Between the Ratio of Oxygen Saturation to Fraction of Inspired Oxygen and the Ratio of Partial Pressure of Oxygen to Fraction of Inspired Oxygen in Detection and Risk Stratification of Pediatric Acute Respiratory Distress Syndrome

Pooja D Lohano et al. Cureus. .

Abstract

Objective: To measure the correlation between the ratio of oxygen saturation to fraction of inspired oxygen [SpO2/FiO2 (SF)] and the ratio of partial pressure of oxygen to fraction of inspired oxygen [PaO2/FiO2 (PF)] among children diagnosed with acute respiratory distress syndrome (ARDS).

Methodology: A cross-sectional study was conducted at the pediatric intensive care unit (PICU), National Institute of Child Health (NICH), Karachi, a tertiary care government hospital, from November 2020 to July 2021. One hundred twenty children (of either gender) having the age range of 2 months to 16 years, admitted to PICU with acute onset of respiratory distress, were included in the study. We measured SpO2, PaO2, FiO2 and calculated SF and PF ratios. SPSS (version 23) (Armonk, NY: IBM Corp) was used to analyze data, and the Spearmen's correlation test was applied to measure the relationship between SF and PF ratios.

Results: A total of 120 children were included, the mean age was 40.58±38.88 months and 67 (55.8%) were males. The mean FiO2 was 76.33%, the mean PaO2 and SpO2 were 100.35 mmHg and 94.37%, respectively. The mean PF ratio was 156.34, and the mean SF ratio was 156.45. There was a strong correlation between the SF ratio and the PF ratio (r=0.688; p=0.001).

Conclusion: This study has shown that there is a strong correlation between the SF and PF ratios, and a statistically substantial agreement has been observed.

Keywords: lung disease; oxygen saturation index; oxygenation index; pao2 /fio2; pediatric acute respiratory distress syndrome; picu; pulse oximetry; spo2/fio2.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Frequency distribution of severity of ARDS
ARDS: acute respiratory distress syndrome, OSI: oxygen saturation index, OI: oxygenation index.
Figure 2
Figure 2. Correlation between SF and PF ratios among the study participants
SF: ratio of oxygen saturation to fraction of inspired oxygen; PF: ratio of partial pressure of oxygen to fraction of inspired oxygen.
See this image and copyright information in PMC

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