Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Sep-Oct;26(5):307-310.
doi: 10.4103/jiaps.JIAPS_149_20. Epub 2021 Sep 16.

Evaluation of Risk Factors Affecting Outcome in Outborn Surgical Neonates

Anup Mohta  1 , Ashwani Mishra  1 , Niyaz A Khan  1 , Mamta Jajoo  2 , Sujoy Neogi  1 , Mamta Sengar  1 , Chhabi Ranu Gupta  1
Affiliations

Evaluation of Risk Factors Affecting Outcome in Outborn Surgical Neonates

Anup Mohta et al. J Indian Assoc Pediatr Surg. 2021 Sep-Oct.

Abstract

Background: Mortality in surgical neonates contributes to neonatal mortality rates. The study was conceptualized to study clinical and nonclinical factors affecting mortality in surgical neonates so that timely intervention could result in improved survival of the neonates.

Materials and methods: The study was initiated after approval from the institutional ethics committee and included 120 surgical neonates over a period of 18 months after obtaining consent from the parents/caregivers. Predesigned pro forma was used to record the details of antenatal care received, place of birth, travel history, maternal education and gestational age, and clinical condition at the time of admission. Values of biochemical tests such as serum electrolytes, serum creatinine, and arterial blood gasses were recorded. The need of inotrope support, blood or blood product transfusion, and postoperative ventilator support and intensive care unit (ICU) care was recorded. The results of the two groups, i.e., survivals and mortality, were compared. Outcome was recorded as mortality at 30 days or earlier.

Results: Irrespective of the surgical condition, the survival rate was significantly better in those babies who weighed more than 2.5 kg at the time of admission, had capillary refill time of <3 s, had serum ionized calcium levels more than 1 mmol/L, and did not require inotropes, blood or blood product transfusion, and postoperative ICU care and ventilator support. The place of birth, educational status of the mother, gestational age, and distance traveled for care had no statistically significant effect on survival.

Conclusion: There is a statistically significant correlation between the survival of the babies who weighed more than 2.5 kg and are more physiologically preserved at the time of admission. Mortality rates can be decreased by timely interventions to reduce the need of inotropes, blood or blood products, and ICU care and ventilator support during their postoperative recovery.

Keywords: Clinical; nonclinical parameters; outborn neonates; surgical neonates.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

References

    1. Bhatnagar SN, Sarin YK. Current trends in neonatal surgery in India. J Neonatal Surg. 2012;1:18. - PMC - PubMed
    1. Gangopadhyay AN, Upadhyaya VD, Sharma SP. Neonatal surgery: A ten year audit from a university hospital. Indian J Pediatr. 2008;75:1025–30. - PubMed
    1. Paul VK, Kumar R, Zodpey S. Towards single digit neonatal mortality rate in India. J Perinatol. 2016;36:51–2. - PubMed
    1. Sowande OA, Ogundoyin OO, Adejuyigbe O. Pattern and factors affecting management outcome of neonatal emergency surgery in Ile-Ife, Nigeria. Surg Pract. 2007;11:71–5.
    1. Gizaw M, Molla M, Mekonnen W. Trends and risk factors for neonatal mortality in Butajira District, South Central Ethiopia, (1987-2008): A prospective cohort study. BMC Pregnancy Childbirth. 2014;14:64. - PMC - PubMed