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Multicenter Study
. 2021 Nov 1;116(11):2296-2299.
doi: 10.14309/ajg.0000000000001502.

Vulvar Crohn's Disease: Clinical Features and Outcomes

Janice M Cho  1 , Edward V Loftus Jr  2 , David H Bruining  2 , Victor G Chedid  2 , Francis A Farraye  3 , William A Faubion Jr  2 , Amanda M Johnson  2 , Sunanda V Kane  2 , John B Kisiel  2 , Talha A Malik  4 , Konstantinos A Papadakis  2 , Darrell S Pardi  2 , Michael F Picco  3 , Laura E Raffals  2 , Kenneth W Schroeder  2 , William J Tremaine  2 , Nayantara Coelho-Prabhu  2
Affiliations
Multicenter Study

Vulvar Crohn's Disease: Clinical Features and Outcomes

Janice M Cho et al. Am J Gastroenterol. .

Abstract

Introduction: Vulvar involvement is a rare complication of Crohn's disease (CD). The optimal treatment of vulvar CD is unknown.

Methods: We conducted a 25-year retrospective cohort study of vulvar CD from 3 referral centers. Clinical features and outcomes were studied.

Results: Fifty patients were identified. The most common vulvar symptoms were pain (74%), edema (60%), ulcerations (46%), nodules (36%), and abscess (34%). Medical management leading to symptomatic improvement varied, and 5 patients ultimately required surgery.

Discussion: Vulvar CD manifests with a broad spectrum of symptoms. Aggressive medical management was frequently effective, although surgery was required in 10% of cases.

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