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. 2021 Sep 20;56(5):647-655.
doi: 10.1055/s-0041-1731657. eCollection 2021 Oct.

Thromboembolism in Arthroplasty: Compliance to Prophylaxis

Leandra Marla Aires Travassos Viana  1 , Iara Antônia Lustosa Nogueira  1 , Andréa Martins Melo Fontenele  2 , Liszt Palmeira de Oliveira  3
Affiliations

Thromboembolism in Arthroplasty: Compliance to Prophylaxis

Leandra Marla Aires Travassos Viana et al. Rev Bras Ortop (Sao Paulo). .

Abstract

Objective The present paper aims to identify the profile of compliance to thromboembolism drug prophylaxis in patients undergoing knee or hip arthroplasty at a public hospital. Methods This is a prospective cohort study, carried out from August 2017 to September 2018, with adult patients who were followed-up from admission until the postoperative period. The Morisky Medication Adherence Scale, consisting of eight items, was applied. Compliance was quantified according to the sum of all correct answers as high (8 points), medium (6 to < 8 points), and low compliance (< 6 points). For the present study, subjects with high compliance were referred as highly compliant, whereas those with medium to low compliance were referred as partially compliant. Results The compliance analysis showed that 73.0% of the patients were highly compliant and 27.0% were partially compliant to thromboprophylaxis. The anticoagulant prescribed at hospital discharge was rivaroxaban, a direct factor Xa inhibitor. Compliance was greater in patients who did not require reinforcement in prophylaxis guidance during follow-up; these subjects reported good and excellent acceptance of prophylaxis, although they were on multiple medications at discharge. Conclusion The data analysis allowed us to conclude that the factors that most influenced compliance were the levels of understanding and acceptance of prophylaxis by the patients, the amount of medication used per day by the subject, the cost of the anticoagulant agent, and its potential to cause adverse reactions.

Keywords: anticoagulants; arthroplasty; prophylaxis; thromboembolism; treatment adherence.

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Conflict of interest statement

Conflito de Interesses Os autores declaram não haver conflito de interesses.

Figures

Fig. 1
Fig. 1
Flow chart for sample determination.
Fig. 2
Fig. 2
Main reported adverse reactions to the anticoagulant agent.
Fig. 1
Fig. 1
Fluxograma para determinação da amostra.
Fig. 2
Fig. 2
Principais reações adversas relatadas.
See this image and copyright information in PMC

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