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. 2021 Nov;26(44):2100977.
doi: 10.2807/1560-7917.ES.2021.26.44.2100977.

Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021

Brechje de Gier  1 , Stijn Andeweg  1 , Jantien A Backer  1 ; RIVM COVID-19 surveillance and epidemiology team  2 ; Susan Jm Hahné  1 , Susan van den Hof  1 , Hester E de Melker  1 , Mirjam J Knol  1 ; RIVM COVID-19 surveillance and epidemiology team (in addition to the named authors)
Collaborators, Affiliations

Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021

Brechje de Gier et al. Euro Surveill. 2021 Nov.

Abstract

We estimated SARS-CoV-2 vaccine effectiveness against onward transmission by comparing secondary attack rates among household members for vaccinated and unvaccinated index cases, based on source and contact tracing data collected when the Delta variant was dominant. Effectiveness of full vaccination of the index case against transmission to unvaccinated and fully vaccinated household contacts, respectively, was 63% (95% confidence interval (CI): 46-75) and 40% (95% CI: 20-54), in addition to the direct protection of vaccination of contacts against infection.

Keywords: COVID-19; SARS-CoV-2; household study; transmission; vaccine effectiveness.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure
Figure
Notifications of positive SARS-CoV-2 tests per day by symptom onset, and percentage of the population fully vaccinateda, the Netherlands, 13 November 2020–24 September 2021 (n = 1,554,825)
See this image and copyright information in PMC

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