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Review
. 2021 Dec;14(4):723-735.
doi: 10.1016/j.path.2021.06.012. Epub 2021 Oct 7.

Osteofibrous Dysplasia and Adamantinoma

Alessandra F Nascimento  1 , Scott E Kilpatrick  2 , John D Reith  3
Affiliations
Review

Osteofibrous Dysplasia and Adamantinoma

Alessandra F Nascimento et al. Surg Pathol Clin. 2021 Dec.

Abstract

For decades, the diagnosis, treatment, and even pathogenesis of the osteofibrous dysplasia/osteofibrous dysplasia-like adamantinoma/classic adamantinoma spectrum of neoplasms have been controversial. Herein, we discuss and illustrate the radiographic and histologic spectrum, differential diagnoses, unifying chromosomal and molecular abnormalities, and current controversies and treatment recommendations for each entity.

Keywords: Adamantinoma; Dedifferentiated adamantinoma; OFD-like adamantinoma; Osteofibrous dysplasia.

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Conflict of interest statement

Disclosure The authors have nothing to disclose.

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