Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Sep 30;34(3):252-258.

Rifle Criteria For Acute Kidney Injury In Burn Patients: Prevalence And Risk Factors

O N Putra  1 , I D Saputro  2 , D Diana  1
Affiliations

Rifle Criteria For Acute Kidney Injury In Burn Patients: Prevalence And Risk Factors

O N Putra et al. Ann Burns Fire Disasters. .

Abstract
in English, French

Acute kidney injury is one of the severe complications after burns. The purpose of this study was to identify prevalence, risk factors to the development of acute kidney injury (AKI) in burn patients and mortality, using RIFLE classification: risk (R), injury (I), failure (F), loss (L), and end-stage kidney disease (E). This 3-year retrospective study was conducted in burn patients admitted to the Dr. Soetomo Hospital Burn Center between January 2018 and September 2020. Burn patients aged >18 years old and diagnosed with acute kidney injury during hospitalization were enrolled in this study. Factors influencing AKI and its mortality were assessed using bivariate and multivariate logistic regression analysis. Eighty-nine burn patients were available for analysis, and 18 (20%) of them developed AKI according to the RIFLE classification: risk in 6 (33%), injury in 7 (39%) and failure in 5 (28%). Patients with AKI had a significantly higher age and % of TBSA than those without AKI (p-value <0.05). Age more than 60 years old was significantly associated as a risk factor to develop AKI (OR=25.553, p value=0.014). The mortality rate of patients with AKI was 83% (15 deaths from 18 patients), with the overall mortality of patients 16.8%. Chi-square analysis indicated inhalation injury, % of TBSA, and age as risk factors for mortality (p-value < 0.05). The conclusion of our study was that the incidence of AKI in burn patients was relatively high. Older age as a risk factor to develop AKI and inhalation injury, TBSA, and age were associated with mortality.

La défaillance rénale aiguë (DRA) est une des complications graves des brûlures. Cette étude a pour d’évaluer sa prévalence, les facteurs de risque de sa survenue et sa mortalité, en utilisant la classification RIFLE : R (Risk- Risque), I (Injury- Lésion), F (Failure- Défaillance), L (Loss- Perte de fonction), E (End stage- Terminale). Cette étude rétrospective a concerné les patients hospitalisés dans le CTB de l’hôpital Dr Soetomo durant 3 ans (janvier 2018- décembre 2020). Elle a concerné tous les patients de plus de 18 ans ayant subi une DRA. Les facteurs de risque ont été évalués par analyses uni- et multivariées. Quatre- vingt- dix- neuf patients étaient éligibles, dont 18 ont développé une DRA (6- 33%- R ; 7- 39%- I et 5- 28%- F). Les patients avec DRA étaient plus âgés et brûlés plus extensivement, en particulier, l’âge de plus de 60 ans avait un OR de 25,553 ; p= 0,014). La mortalité des patients avec DRA était de 83% (15 morts sur 18) alors que la mortalité globale était de 16,8%. L’analyse par C² montrait que l’âge, la surface brûlée et l’inhalation de fumée étaient des facteurs de mortalité (p<0,05). L’incidence de DRA est relativement élevée et corrèle avec l’âge quand la mortalité globale reste liée à l’âge, la surface brûlée et l’inhalation de fumées.

Keywords: AKI; RIFLE; burn patients; mortality; prevalence.

PubMed Disclaimer

Figures

Table I
Table I. RIFLE criteria for AKI classification
Table II
Table II. Demographic data of burn patients
Table III
Table III. Complications among burn patients with AKI
Fig. 1
Fig. 1. Pearson correlation between percentage of TBSA and albumin level
Table IV
Table IV. Creatinine and BUN level between AKI patients
Table V
Table V. Bivariate analysis factors related to developing AKI
Table VI
Table VI. Risk factors for developing AKI by multivariate logistic regression
Fig. 2
Fig. 2. ROC curve
Table VII
Table VII. Bivariate analysis associated with mortality
See this image and copyright information in PMC

References

    1. Rudal N, Green A. Burns: clinical features and prognosis. Pharmaceutical Journal. 2010;2:245–245.
    1. Schneider DF, Dobrowolsky A, Shakir IA. Predicting acute kidney injury among burn patients in the 21st century: a classification and regression tree analysis. J Burn Care Res. 2012;33:242–251. - PMC - PubMed
    1. Emara S, Alzaylai A. Renal failure in burn patients: a review. Ann Burns Fire Disasters. 2013;26(1):12–15. - PMC - PubMed
    1. Kellum JA. How can we define recovery after acute kidney injury? Considerations from epidemiology and clinical trial design. Nephron Clin Pract. 2014;127:81–88. - PubMed
    1. KDIGO: Clinical Practice Guideline for Acute Kidney Injury. Official Journal of the International Society of Nephrology. 2012;2(1)

LinkOut - more resources