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Case Reports
. 2022 Feb;58(1):43-50.
doi: 10.23736/S1973-9087.21.06886-6. Epub 2021 Nov 8.

Modified constraint induced movement therapy in children with obstetric brachial plexus palsy: a systematic review

Affiliations
Case Reports

Modified constraint induced movement therapy in children with obstetric brachial plexus palsy: a systematic review

Monica Sicari et al. Eur J Phys Rehabil Med. 2022 Feb.

Abstract

Introduction: Obstetric brachial plexus palsy (OBPP) is a flaccid paralysis occurring in the upper limb during birth. The OBPP includes mild lesions with complete spontaneous recovery and severe injuries with no regain of arm function. Among the most promising rehabilitation treatments aimed at improving upper extremity motor activities in individuals with neurological dysfunctions, there is the modified constraint-induced movement therapy (mCIMT). The aim of this systematic review is to assess and synthesize the critical aspects of the use of mCIMT in children with OBPP.

Evidence acquisition: This systematic review has been carried out according to the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analysis). A comprehensive search of the literature was conducted using PubMed, MEDLINE and Evidence Based Medicine Reviews, databases. We enclosed experimental and original articles, case reports and book chapters. Four articles were finally included.

Evidence synthesis: One case report tested the feasibility of mCIMT to encourage use of the affected arm in a child with Erb-Duchenne palsy and documented the clinical changes observed. A case series had the purpose to determine if mCIMT in combination with botulinum toxin (BTX-A) improved arm function in 2 children with OBPP. A cohort study compared the use of mCIMT in 19 OBPP and 18 unilateral Cerebral Palsy. A prospective single-blind RCT described mCIMT versus conventional therapy in a group of 39 children with OBPP.

Conclusions: This systematic review on the use of mCIMT in children with OBPP shows that there is unanimous agreement that a program should last 2 weeks at least. However, there is no scientific evidence supporting a single common mCIMT protocol in the management of OBPP because of a considerable heterogeneity. Further high methodological studies regarding the application of mCIMT for OBPP and based on larger patients' sample should have the potential to optimize the appropriateness of care provided to infants with OBPP and, therefore, their quality of life.

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Conflict of interest statement

Conflicts of interest.—The authors certify that there is no conflict of interest with any financial organization regarding the material discussed in the manuscript.

Figures

Figure 1
Figure 1
—PRISMA flowchart.

References

    1. Chauhan SP, Blackwell SB, Ananth CV. Neonatal brachial plexus palsy: incidence, prevalence, and temporal trends. Semin Perinatol 2014;38:210–8. https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&l... 10.1053/j.semperi.2014.04.007 - DOI - PubMed
    1. Yang LJ. Neonatal brachial plexus palsy—management and prognostic factors. Semin Perinatol 2014;38:222–34. https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&l... 10.1053/j.semperi.2014.04.009 - DOI - PubMed
    1. DeFrancesco CJ, Shah DK, Rogers BH, Shah AS. The Epidemiology of Brachial Plexus Birth Palsy in the United States: Declining Incidence and Evolving Risk Factors. J Pediatr Orthop 2019;39:e134–40. https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&l... 10.1097/BPO.0000000000001089 - DOI - PubMed
    1. Smania N, Berto G, La Marchina E, Melotti C, Midiri A, Roncari L, et al. Rehabilitation of brachial plexus injuries in adults and children. Eur J Phys Rehabil Med 2012;48:483–506. https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&l... - PubMed
    1. Zafeiriou DI, Psychogiou K. Obstetrical brachial plexus palsy. Pediatr Neurol 2008;38:235–42. https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&l... 10.1016/j.pediatrneurol.2007.09.013 - DOI - PubMed