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. 1987 May;55(5):567-9.
doi: 10.1038/bjc.1987.115.

Value of CA 15:3 in the follow-up of breast cancer patients

D M Pons-Anicet, B P Krebs, R Mira, M Namer
Free PMC article

Value of CA 15:3 in the follow-up of breast cancer patients

D M Pons-Anicet et al. Br J Cancer. 1987 May.
Free PMC article

Abstract

CA 15:3, a new tumour marker detectable by two monoclonal antibodies (115 D 8 and DF 3), was measured by an immunoradiometric technique on the ELSA solid phase. Sixteen percent of patients with localized breast cancer had CA 15:3 levels greater than 25 U ml-1, and levels increased with tumour size. CA 15:3 levels greater than 25 U ml-1 were found in 54% of patients with nodal involvement and in 91% of patients with metastatic breast disease. Measurement of CA 15:3 in 70 women with metastatic breast cancer and a normal CEA revealed positive CA 15:3 levels at diagnosis of the first metastasis in 66% of cases; 63% of these patients could be monitored with CA 15:3.

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