A New OECD Definition for Per- and Polyfluoroalkyl Substances

Zhanyun Wang¹, Andreas M Buser², Ian T Cousins³, Silvia Demattio⁴, Wiebke Drost⁵, Olof Johansson⁶, Koichi Ohno⁷, Grace Patlewicz⁸, Ann M Richard⁸, Glen W Walker⁹, Graham S White¹⁰, Eeva Leinala¹¹

Affiliations

¹ Chair of Ecological Systems Design, Institute of Environmental Engineering, ETH Zürich, John-von-Neumann-Weg 9, 8093 Zürich, Switzerland.
² Swiss Federal Office for the Environment (FOEN), 3063 Ittigen, Switzerland.
³ Department of Environmental Science and Analytical Chemistry (ACES), Stockholm University, SE-10691, Stockholm, Sweden.
⁴ European Chemicals Agency, Telakkakatu 6, 00150 Helsinki, Finland.
⁵ German Environment Agency, Wörlitzer Platz 1, 06844 Dessau-Roßlau, Germany.
⁶ Swedish Chemicals Agency, Esplanaden 3A, 172 67 Sundbyberg, Sweden.
⁷ Health and Environmental Risk Division, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki 305-8506, Japan.
⁸ Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, Durham, North Carolina 27711, United States.
⁹ Department of Agriculture, Water and the Environment, Australian Government, General Post Office Box 858, Canberra, Australian Capital Territory 2601, Australia.
¹⁰ New Substances Assessment and Control Bureau, Safe Environments Directorate, Health Canada, Ottawa K1A 0K9, Canada.
¹¹ Environment, Health and Safety Division, Environment Directorate, Organisation for Economic Cooperation and Development, 2, rue André Pascal, 75016, Paris, France.

PMID: 34751569
DOI: 10.1021/acs.est.1c06896

A New OECD Definition for Per- and Polyfluoroalkyl Substances

Zhanyun Wang et al. Environ Sci Technol. 2021.

. 2021 Dec 7;55(23):15575-15578.

doi: 10.1021/acs.est.1c06896. Epub 2021 Nov 9.

Authors

Affiliations

¹ Chair of Ecological Systems Design, Institute of Environmental Engineering, ETH Zürich, John-von-Neumann-Weg 9, 8093 Zürich, Switzerland.
² Swiss Federal Office for the Environment (FOEN), 3063 Ittigen, Switzerland.
³ Department of Environmental Science and Analytical Chemistry (ACES), Stockholm University, SE-10691, Stockholm, Sweden.
⁴ European Chemicals Agency, Telakkakatu 6, 00150 Helsinki, Finland.
⁵ German Environment Agency, Wörlitzer Platz 1, 06844 Dessau-Roßlau, Germany.
⁶ Swedish Chemicals Agency, Esplanaden 3A, 172 67 Sundbyberg, Sweden.
⁷ Health and Environmental Risk Division, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki 305-8506, Japan.
⁸ Center for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, Durham, North Carolina 27711, United States.
⁹ Department of Agriculture, Water and the Environment, Australian Government, General Post Office Box 858, Canberra, Australian Capital Territory 2601, Australia.
¹⁰ New Substances Assessment and Control Bureau, Safe Environments Directorate, Health Canada, Ottawa K1A 0K9, Canada.
¹¹ Environment, Health and Safety Division, Environment Directorate, Organisation for Economic Cooperation and Development, 2, rue André Pascal, 75016, Paris, France.

PMID: 34751569
DOI: 10.1021/acs.est.1c06896

No abstract available

Keywords: PFAS definition; PFAS synthesis; PFAS terminology; PFAS universe; cheminformatic tools.

PubMed Disclaimer

Cited by

PFOS Impairs Mitochondrial Biogenesis and Dynamics and Reduces Oxygen Consumption in Human Trophoblasts.
Hofmann A, Mishra JS, Yadav P, Dangudubiyyam SV, Blesson CS, Kumar S. Hofmann A, et al. J Environ Sci Public Health. 2023;7(4):164-175. Epub 2023 Oct 10. J Environ Sci Public Health. 2023. PMID: 37920428 Free PMC article.
Cross-cutting studies of per- and polyfluorinated alkyl substances (PFAS) in Arctic wildlife and humans.
Lohmann R, Abass K, Bonefeld-Jørgensen EC, Bossi R, Dietz R, Ferguson S, Fernie KJ, Grandjean P, Herzke D, Houde M, Lemire M, Letcher RJ, Muir D, De Silva AO, Ostertag SK, Rand AA, Søndergaard J, Sonne C, Sunderland EM, Vorkamp K, Wilson S, Weihe P. Lohmann R, et al. Sci Total Environ. 2024 Dec 1;954:176274. doi: 10.1016/j.scitotenv.2024.176274. Epub 2024 Sep 18. Sci Total Environ. 2024. PMID: 39304148 Review.
Development of PFAS-Free Locally Concentrated Ionic Liquid Electrolytes for High-Energy Lithium and Aluminum Metal Batteries.
Liu X, Xu C, Adenusi H, Wu Y, Passerini S. Liu X, et al. Acc Chem Res. 2025 Feb 4;58(3):354-365. doi: 10.1021/acs.accounts.4c00653. Epub 2025 Jan 26. Acc Chem Res. 2025. PMID: 39863994 Free PMC article.
Freshwater ecotoxicity characterization factors for PFASs.
Aggarwal R. Aggarwal R. Integr Environ Assess Manag. 2025 Jan 1;21(1):208-219. doi: 10.1093/inteam/vjae013. Integr Environ Assess Manag. 2025. PMID: 39879214 Free PMC article.
Practical application guide for the discovery of novel PFAS in environmental samples using high resolution mass spectrometry.
Strynar M, McCord J, Newton S, Washington J, Barzen-Hanson K, Trier X, Liu Y, Dimzon IK, Bugsel B, Zwiener C, Munoz G. Strynar M, et al. J Expo Sci Environ Epidemiol. 2023 Jul;33(4):575-588. doi: 10.1038/s41370-023-00578-2. Epub 2023 Jul 29. J Expo Sci Environ Epidemiol. 2023. PMID: 37516787 Free PMC article.

See all "Cited by" articles

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- American Chemical Society

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

A New OECD Definition for Per- and Polyfluoroalkyl Substances

Affiliations

A New OECD Definition for Per- and Polyfluoroalkyl Substances

Authors

Affiliations

Similar articles

Cited by

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources