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Review
. 2021 Dec;42(Suppl 2):155-159.
doi: 10.1007/s00292-021-01019-3. Epub 2021 Nov 9.

[Updated WHO classification of tumors of the breast]

[Article in German]
Annette Lebeau  1   2
Affiliations
Review

[Updated WHO classification of tumors of the breast]

[Article in German]
Annette Lebeau. Pathologe. 2021 Dec.

Abstract
in English, German

In the fifth edition of the World Health Organization (WHO) classification of tumors of the breast, the histological features of the lesions continue to form the basis of the classification; however, molecular pathology nowadays provides approaches for improved diagnostics and prediction of prognosis and treatment response, which have been incorporated into the update of the classification. The most important changes are presented, which include changes in the histological classification of invasive carcinomas, the subtyping of lobular carcinoma in situ (LCIS) and the dignity criteria of phyllodes tumors.

Auch in der 5. Auflage der World Health Organization- (WHO-)Klassifikation der Tumoren der Mamma bilden die histologischen Merkmale der Läsionen die Basis der Klassifikation. Allerdings liefert die molekulare Pathologie heutzutage Ansätze für eine verbesserte Diagnostik und Vorhersage der Prognose und des Therapieansprechens, die in die Aktualisierung der Klassifikation eingeflossen sind. Der Beitrag stellt die wichtigsten Änderungen vor. Hierzu zählen Änderungen in der histologischen Klassifikation der invasiven Karzinome, der Subtypisierung des lobulären Carcinoma in situ (LCIS) und den Dignitätskriterien von Phylloidestumoren.

Keywords: Carcinoma in situ; Diagnostic; Phyllodes tumor; Prediction; Prognosis.

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References

Literatur

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