Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jan;66(1):68-73.
doi: 10.1007/s10384-021-00884-y. Epub 2021 Nov 9.

Corneal endothelial cell damage after scleral fixation of intraocular lens surgery

Yeon Ji Jo  1 , Jong Soo Lee  1 , Ik Soo Byon  1 , Ji Eun Lee  2 , Sung Who Park  3
Affiliations

Corneal endothelial cell damage after scleral fixation of intraocular lens surgery

Yeon Ji Jo et al. Jpn J Ophthalmol. 2022 Jan.

Abstract

Purpose: To analyze corneal endothelial cell damage after scleral fixation of intraocular lens (SFIOL) surgery.

Study design: Retrospective study.

Methods: Medical records of consecutive eyes undergoing SFIOL surgery performed by a single surgeon were reviewed between January 2011 and June 2019. The patients were classified into three groups according to surgical methods: Group I, re-fixating the existing intraocular lens (IOL) or fixating a new IOL in an aphakic eye; Group II, removing the existing IOL and fixating a new IOL; and Group III, phacoemulsification and fixating a new IOL simultaneously. Preoperative and postoperative specular microscopy (SM) status were compared. Changes in SM were compared among the three groups.

Results: Ninety-four eyes were included. Thirty-four eyes in Group I, 39 in Group II, and 21 in Group III. The endothelial cell density (ECD) loss in Group I was 1.5%, less than the ECD loss of 14.3% (p < 0.001) in Group II and 15.4% (p = 0.005), in Group III. In no eye was there an ECD decrease to < 1000/mm2 following the surgical procedure.

Conclusions: ECD loss was related to IOL removal or phacoemulsification rather than SFIOL surgery. SFIOL using the existing IOL should be considered preferential in eyes with low ECD and dislocated IOL.

Keywords: Aphakia; Dislocated intraocular lens; Endothelial cell density; Phacoemulsification; Scleral fixation.

PubMed Disclaimer

References

    1. Jacob S, Kumar DA, Rao NK. Scleral fixation of intraocular lenses. Curr Opin Ophthalmol. 2020;31:50–60. - DOI
    1. Baykara M. Suture burial technique in scleral fixation. J Cataract Refract Surg. 2004;30:957–9. - DOI
    1. Lee Y, Kim MH, Park YL, Na KS, Kim HS. Comparison of short-term clinical outcomes between scleral fixation vs. iris fixation of dislocated IOL. J Korean Ophthalmol Soc. 2017;58:1131–7. - DOI
    1. Waring GO, Bourne WM, Edelhauser HF, Kenyon KR. The corneal endothelium. Normal and pathologic structure and function. Ophthalmology. 1982;89:531–90. - DOI
    1. Bourne WM, Nelson LR, Hodge DO. Central corneal endothelial cell changes over a ten-year period. Invest Ophthalmol Visl Sci. 1997;38:779–82.

LinkOut - more resources