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. 2021 Aug 13;14(11):2446-2448.
doi: 10.1093/ckj/sfab147. eCollection 2021 Nov.

Longevity and correlation with disease severity of the humoral and cellular response to SARS-CoV-2 infection in haemodialysis patients

An S De Vriese  1 , Jens Van Praet  1 , Marijke Reynders  2 , Line Heylen  3 , Liesbeth Viaene  4 , Rogier Caluwé  5 , Melanie Schoutteten  3 , Dirk De Bacquer  6
Affiliations

Longevity and correlation with disease severity of the humoral and cellular response to SARS-CoV-2 infection in haemodialysis patients

An S De Vriese et al. Clin Kidney J. .
No abstract available

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Figures

FIGURE 1:
FIGURE 1:
SARS-CoV-2 (A) anti-S IgG titres, (B) anti-N IgG titres and (C) QuantiFERON response in HD patients with a history of PCR-confirmed SARS-CoV-2 infection that had asymptomatic or mild disease (blue circles) or severe disease (red circles) as a function of the time interval between the lowest cycle threshold value and serum sampling. Anti-S IgG was measured by a chemiluminescent microparticle immunoassay (CMIA) on the ARCHITECT i System (SARS-CoV-2 IgG II Quant assay, Abbott Laboratories, Abbott Park, IL, USA). The cut-off for positivity (dashed line) was 50 AU/mL and the conversion factor to the World Health Organization binding antibody units (BAU/mL) is BAU/mL = 0.142 × AU/mL. Anti-N IgG was measured by a CMIA on the same ARCHITECT i analyser (SARS-CoV-2 IgG assay, Abbott). A signal:cut-off ratio ≥1.4 (dashed line) was interpreted as reactive. The QuantiFERON SARS-CoV-2 test (Qiagen, Venlo, The Netherlands) measures the secretion of interferon-γ by peripheral blood CD4+ and CD8+ lymphocytes upon SARS-CoV-2 glycoprotein stimulation. The threshold for positivity (dashed line) is 0.15 IU/mL.
See this image and copyright information in PMC

References

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