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Comment
. 2022 Apr;65(4):849-850.
doi: 10.1007/s11427-021-2022-5. Epub 2021 Nov 5.

Treatment of COVID-19 with MSCs: how does it work?

Affiliations
Comment

Treatment of COVID-19 with MSCs: how does it work?

Armand Keating. Sci China Life Sci. 2022 Apr.
No abstract available

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Comment on

  • Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms.
    Zhu R, Yan T, Feng Y, Liu Y, Cao H, Peng G, Yang Y, Xu Z, Liu J, Hou W, Wang X, Li Z, Deng L, Wang S, Li J, Han Q, Li H, Shan G, Cao Y, An X, Yan J, Zhang Z, Li H, Qu X, Zhu J, Zhou S, Wang J, Zhang F, Gao J, Jin R, Xu D, Ma YQ, Huang T, Peng S, Zheng Z, Stambler I, Gilson E, Lim LW, Moskalev A, Cano A, Chakrabarti S, Ulfhake B, Su H, Xu H, Xu S, Wei F, Brown-Borg HM, Min KJ, Ellison-Hughes G, Caruso C, Jin K, Zhao RC. Zhu R, et al. Cell Res. 2021 Dec;31(12):1244-1262. doi: 10.1038/s41422-021-00573-y. Epub 2021 Oct 26. Cell Res. 2021. PMID: 34702946 Free PMC article.

References

    1. Keating A. Mesenchymal stromal cells: new directions. Cell Stem Cell. 2012;10:709–716. doi: 10.1016/j.stem.2012.05.015. - DOI - PubMed
    1. Leng Z, Zhu R, Hou W, Feng Y, Yang Y, Han Q, Shan G, Meng F, Du D, Wang S, et al. Transplantation of ACE2 mesenchymal stem cells improves the outcome of patients with COVID-19 pneumonia. Aging Dis. 2020;11:216. doi: 10.14336/AD.2020.0228. - DOI - PMC - PubMed
    1. Middleton EA, He XY, Denorme F, Campbell RA, Ng D, Salvatore SP, Mostyka M, Baxter-Stoltzfus A, Borczuk AC, Loda M, et al. Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome. Blood. 2020;136:1169–1179. doi: 10.1182/blood.2020007008. - DOI - PMC - PubMed
    1. Moll G, Ankrum JA, Kamhieh-Milz J, Bieback K, Ringdén O, Volk HD, Geissler S, Reinke P. Intravascular mesenchymal stromal/stem cell therapy product diversification: time for new clinical guidelines. Trends Mol Med. 2019;25:149–163. doi: 10.1016/j.molmed.2018.12.006. - DOI - PubMed
    1. Shahani P, Datta I. Mesenchymal stromal cell therapy for coronavirus disease 2019: which? when? and how much? Cytotherapy. 2021;23:861–873. doi: 10.1016/j.jcyt.2021.04.004. - DOI - PMC - PubMed