Complex infections in vivax malaria: the more you look, the more you find
- PMID: 34756507
- DOI: 10.1016/j.pt.2021.10.002
Complex infections in vivax malaria: the more you look, the more you find
Abstract
The human malaria parasite Plasmodium vivax commonly causes complex multiclonal infections. Recently, Dia et al. have developed innovative methods for single-cell sequencing (SCS) of P. vivax infections by adapting an approach used previously for Plasmodium falciparum. Their studies provide fascinating new insights into P. vivax intrahost diversity and evolution.
Keywords: Plasmodium vivax; genotyping; malaria; single-cell sequencing; whole-genome sequencing.
Copyright © 2021. Published by Elsevier Ltd.
Conflict of interest statement
Declaration of interests The author declares no competing interests.
Comment on
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Single-genome sequencing reveals within-host evolution of human malaria parasites.Cell Host Microbe. 2021 Oct 13;29(10):1496-1506.e3. doi: 10.1016/j.chom.2021.08.009. Epub 2021 Sep 6. Cell Host Microbe. 2021. PMID: 34492224 Free PMC article.
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