Towards a Rational Balanced Pancreatic and Islet Allocation Schema
- PMID: 34757859
- PMCID: PMC8586185
- DOI: 10.1177/09636897211057130
Towards a Rational Balanced Pancreatic and Islet Allocation Schema
Abstract
Allocation of donated organs for transplantation is a complex process that considers numerous factors such as donor, organ and candidate characteristics and practical issues such as geography. Whole pancreas and isolated islet transplantation are lifesaving for certain individuals with diabetes. Herein, we suggest a revised allocation schema that matches donor characteristics with candidate medical condition while allowing for geographic considerations. It is hoped that adoption of this schema will shorten allocation time, decrease organ waste and optimize the parity between organ donor characteristics and candidate state of health.
Keywords: allocation criteria; pancreatic and islet transplantation; type 1 diabetes.
Conflict of interest statement
References
-
- Rudolph EN, Dunn TB, Sutherland DER, Kandaswamy R, Finger EB. Optimizing outcomes in pancreas transplantation: impact of organ preservation time. Clin Transplant. 2017;31(9). - PubMed
-
- Hilling DE, Bouwman E, Terpstra OT, Marang van de Mheen PJ. Effects of donor-, pancreas-, and isolation-related variables on human islet isolation outcome: a systematic review. Cell Transplant. 2014;23(8):921–928. - PubMed
-
- Benhamou PY, Watt PC, Mullen Y, Ingles S, Watanabe Y, Nomura Y, Hober C, Miyamoto M, Kenmochi T, Passaro EP. Human islet isolation in 104 consecutive cases. factors affecting isolation success. Transplantation. 1994;57(12):1804–1810. - PubMed
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