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Case Reports
. 2021;12(Suppl 2):S421-S425.
doi: 10.22088/cjim.12.0.421.

Adult Wilms with Biphasic Pattern; A Case Report

Mahdi Farzadnia  1 , Mahboobe Karrabi  1 , Hamidreza Ghorbani  2
Affiliations
Case Reports

Adult Wilms with Biphasic Pattern; A Case Report

Mahdi Farzadnia et al. Caspian J Intern Med. 2021.

Abstract

Background: Wilms' tumor, nephroblastoma, is an extremely uncommon kidney tumor of adulthood. We reported a woman with a huge kidney mass diagnosed with nephroblastoma.

Case presentation: A 39-year-old female was assessed due to right flank pain. CT scan revealed a mass measuring 128×100 mms involving the upper portion of the right kidney. The patient underwent nephrectomy, and the diagnosis of adult Wilms' tumor was confirmed based on the morphological and immunohistochemical findings.

Conclusion: In adult patients with flank pain and renal mass, the diagnosis of Wilms' tumor should be pronounced in the absence of histopathologic features of renal cell carcinoma.

Keywords: Adult; Case report; Nephroblastoma; Wilms tumor.

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Figures

Figure 2
Figure 2
Wilms’ tumor composed of tubuloglandular and mesenchymal component. A) (40×, H&E stain). B) (200×, H&E stain).C) rosette- like structure (400×, H&E stain). D) mesenchymal stroma (400×, H&E stain)
Figure 3
Figure 3
Immunohistochemical staining A) WT1 B) WT1 (repeat)
Figure 4
Figure 4
Immunohistochemical staining A) Chromogranin B) Synaptophysin C) EMA D) CK E) CD10 F) HMB45 G) CD 56
See this image and copyright information in PMC

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