Autoimmunity in neurodegeneration

Maria Krot^{1

2}, Asya Rolls^{1

2}

Affiliations

¹ Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
² Department of Neuroscience, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

Comment

Maria Krot et al. Science. 2021.

. 2021 Nov 12;374(6569):823-824.

doi: 10.1126/science.abm4739. Epub 2021 Nov 11.

Maria Krot^{1

2}, Asya Rolls^{1

2}

¹ Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
² Department of Neuroscience, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

Abstract

A signaling axis in adaptive immunity is a potential target in Lewy body dementia.

CD4⁺ T cells contribute to neurodegeneration in Lewy body dementia.
Gate D, Tapp E, Leventhal O, Shahid M, Nonninger TJ, Yang AC, Strempfl K, Unger MS, Fehlmann T, Oh H, Channappa D, Henderson VW, Keller A, Aigner L, Galasko DR, Davis MM, Poston KL, Wyss-Coray T. Gate D, et al. Science. 2021 Nov 12;374(6569):868-874. doi: 10.1126/science.abf7266. Epub 2021 Oct 14. Science. 2021. PMID: 34648304 Free PMC article.