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Observational Study
. 2021 Nov 11;21(1):154.
doi: 10.1186/s12894-021-00919-z.

Patients with preoperative asymptomatic pyuria are not prone to develop febrile urinary tract infection after ureteroscopic lithotripsy

Kuan-Jung Lin  1   2 , Eric Y H Huang  3   4 , I-Shen Huang  5   2 , Yu-Hua Fan  5   2 , Chih-Chieh Lin  5   2 , Tzu-Ping Lin  5   2 , Hsiao-Jen Chung  5   2 , Shing-Hwa Lu  5   2 , Junne-Yih Kuo  5   2 , Howard Hung-Hao Wu  5   2 , Yen-Hwa Chang  5   2 , Alex T L Lin  5   2 , William J S Huang  5   2
Affiliations
Observational Study

Patients with preoperative asymptomatic pyuria are not prone to develop febrile urinary tract infection after ureteroscopic lithotripsy

Kuan-Jung Lin et al. BMC Urol. .

Abstract

Background: This study aimed to evaluate the association of asymptomatic pyuria before ureterorenoscopic lithotripsy (URSL) with postoperative febrile urinary tract infection (UTI).

Methods: This observational case-control study identified the patients undergoing URSL for ureteral stones between May 2011 and October 2015. The included patients were classified into two groups: the asymptomatic pyuria group (6-50 white blood cells [WBCs]/high-power field [HPF]) and the non-pyuria group (≤ 5 WBCs/HPF). All data were collected by reviewing medical records. Postoperative outcomes were collected in terms of febrile UTI, emergency visits, and stone-free rate.

Results: A total of 232 patients were included, 101 in the pyuria group, 131 in the non-pyuria group. Two (0.9%) patients developed febrile UTI after URSL and 12 (5.2%) patients visited emergency department for URSL-related symptoms. The overall stone-free rate was 90.9%. There was no significant difference between the pyuria and non-pyuria groups regarding febrile UTI, emergency visits, and stone-free rate. Multivariate analysis revealed that pyuria was neither significantly associated with postoperative febrile UTI (OR = 1.03, 95% CI = 0.06-18.10, P = 0.98), nor with emergency visits (OR = 0.48, 95% CI = 0.13-1.85, P = 0.29).

Conclusions: Compared to the patients with sterile urine prior to URSL, those with asymptomatic pyuria were not prone to develop febrile UTI after URSL.

Keywords: Pyuria; Ureteral stone; Ureterorenoscopic lithotripsy; Urinary tract infections.

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Conflict of interest statement

The authors declare that they have no competing interests.

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