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Comment
. 2021 Nov 11;6(1):391.
doi: 10.1038/s41392-021-00782-2.

Managing stress granule disassembly with ubiquitin and its cousin

Stefan Müller  1
Affiliations
Comment

Managing stress granule disassembly with ubiquitin and its cousin

Stefan Müller. Signal Transduct Target Ther. .
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Heat stress induces polyubiquitylation of SG-associated proteins by an enzymatic E1-E2-E3 cascade. Heat-induced polyubiquitylation prepares cells for the restart of cellular activities upon stress release. The resumption of translation, which is accompanied by the disassembly of SGs is only one critical ubiquitin-regulated process in this recovery phase. Additional processes include the resumption of nucleocytoplasmic transport. The ubiquitin-related SUMO system likely contributes to heat-induced polyubiquitylation of SG-associated proteins (for details see text).
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References

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