Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Feb;59(2):146-152.
doi: 10.1002/uog.24809. Epub 2022 Jan 13.

Does COVID-19 cause pre-eclampsia?

Affiliations
Comment

Does COVID-19 cause pre-eclampsia?

A Khalil et al. Ultrasound Obstet Gynecol. 2022 Feb.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Mechanism of development of pre‐eclampsia in women with COVID‐19. ACE2, angiotensin‐converting enzyme 2; CTB, cytotrophoblast; EVT, extravillous trophoblast; HELLP, hemolysis, elevated liver enzymes and low platelet count; KKS, kinin–kallikrein system; PlGF, placental growth factor; RAS (or RAAS), renin–angiotensin system (or renin–angiotensin–aldosterone system); ROS, reactive oxygen species; (s)Eng, (soluble) endoglin; (s)Flt‐1, (soluble) fms‐like tyrosine kinase‐1; STB, syncytiotrophoblast; TGFβ, transforming growth factor beta; TMPRSS2, transmembrane protease serine 2; VEGF, vascular endothelial growth factor.

Comment on

References

    1. Kc A, Gurung R, Kinney MV, Sunny AK, Moinuddin M, Basnet O, Paudel P, Bhattarai P, Subedi K, Shrestha MP, Lawn JE, Målqvist M. Effect of the COVID‐19 pandemic response on intrapartum care, stillbirth, and neonatal mortality outcomes in Nepal: a prospective observational study. Lancet Glob Health 2020; 8: e1273–1281. - PMC - PubMed
    1. Kumari V, Mehta K, Choudhary R. COVID‐19 outbreak and decreased hospitalisation of pregnant women in labour. Lancet Glob Health 2020; 8: e1116–1117. - PMC - PubMed
    1. RECOVERY Collaborative Group . Convalescent plasma in patients admitted to hospital with COVID‐19 (RECOVERY): a randomised controlled, open‐label, platform trial. Lancet 2021; 397: 2049–2059. - PMC - PubMed
    1. Relph S, Jardine J, Magee LA, von Dadelszen P, Morris E, Ross‐Davie M, Draycott T, Khalil A. Authors' reply re: Maternity services in the UK during the coronavirus disease 2019 pandemic: a national survey of modifications to standard care. BJOG 2021; 128: 937–938. - PMC - PubMed
    1. Chmielewska B, Barratt I, Townsend R, Kalafat E, van der Meulen J, Gurol‐Urganci I, O'Brien P, Morris E, Draycott T, Thangaratinam S, Le Doare K, Ladhani S, von Dadelszen P, Magee L, Khalil A. Effects of the COVID‐19 pandemic on maternal and perinatal outcomes: a systematic review and meta‐analysis. Lancet Glob Health 2021; 9: e759–772. - PMC - PubMed