Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Nov 12;16(11):e0258921.
doi: 10.1371/journal.pone.0258921. eCollection 2021.

Efficacy and safety of manual acupuncture for the treatment of upper limb motor dysfunction after stroke: Protocol for a systematic review and meta-analysis

Di Cao  1 , Xiaolin Zhang  2 , Mingjun Liu  2   3 , Qiguang Yang  1 , Shuhong Gu  1 , Tianjiao Gao  2 , Lin Cong  2 , Dehui Ma  2 , Hongju Lin  1 , Shaotao Chen  2   3
Affiliations

Efficacy and safety of manual acupuncture for the treatment of upper limb motor dysfunction after stroke: Protocol for a systematic review and meta-analysis

Di Cao et al. PLoS One. .

Abstract

Introduction: The incidence of stroke sequelae among patients is as high as 70%-80%. Flexor spasm is the most common stroke sequela, presenting a heavy burden to the patients and their families. This study will evaluate the results of randomized controlled trials to determine the efficacy and safety of hand manipulation acupuncture for the treatment of upper limb motor dysfunction after stroke.

Methods: Eight databases, including China National Knowledge Infrastructure, Chinese Scientific Journal Database, Cochrane Central Register of Controlled Trials, Embase, MEDLINE, PubMed, Wanfang Database, and Web of Science, will be searched using English and Chinese search strategies. In addition, manual retrieval of research papers, conference papers, ongoing experiments, and internal reports, among others, will supplement electronic retrieval. All eligible studies published on or before January 15, 2021 will be selected. To enhance the effectiveness of the study, only clinical randomized controlled trials related to the use of manual acupuncture for the treatment of upper limb motor dysfunction after stroke will be included.

Analysis: The Fugl-Meyer upper extremity assessment will be the primary outcome measure, whereas the Wolf Motor Function Test, Modified Ashworth Scale, arm movement survey test table, and upper extremity freehand muscle strength assessment scores will be the secondary outcomes. Side effects and adverse events will be included as safety evaluations. To ensure the quality of the systematic evaluation, study selection, data extraction, and quality assessment will be independently performed by two authors, and a third author will resolve any disagreement.

Ethics and dissemination: This systematic review will evaluate the efficacy and safety of manual acupuncture for the treatment of upper limb motor dysfunction after stroke. Since all included data will be obtained from published articles, it does not require ethical approval and will be published in a peer-reviewed journal. INPLASY registration number: INPLASY202110071.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. PRISMA flow diagram of study and exclusion.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. GBD 2016 Causes of Death Collaborators. Global, regional, and national age sex specific mortality for 264 causes of death, 1980–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 2017;390:1151–1210. doi: 10.1016/S0140-6736(17)32152-9 - DOI - PMC - PubMed
    1. BROEKS J G, LANKHORST G J, RUMPING K, et al.. The longterm outcome of arm function after stroke: results of a follow-up study. Disabil Rehabil 1999;21 (8):357–364. doi: 10.1080/096382899297459 - DOI - PubMed
    1. Sabini R C, Dijke RSMP, RAGHAVAN P. Stroke survivors talk while doing: development of a therapeutic framework for continued rehabilitation of hand function post strok. J Hand Ther 2013;26 (2):124–130. doi: 10.1016/j.jht.2012.08.002 - DOI - PMC - PubMed
    1. Bleyenheuft Y, GORDON A M. Precision grip in congenital and acquired hemiparesis: similarities in impairments and implications for neurorehabilitation. Front Hum Neurosci 2014;8:459. doi: 10.3389/fnhum.2014.00459 - DOI - PMC - PubMed
    1. Jie Jia. Hand function rehabilitation after stroke. Geriatrics and health care 2015;21(3):129–131.

Publication types

MeSH terms