Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Sep;84(17):6131-5.
doi: 10.1073/pnas.84.17.6131.

The erg gene: a human gene related to the ets oncogene

E S Reddy, V N Rao, T S Papas

The erg gene: a human gene related to the ets oncogene

E S Reddy et al. Proc Natl Acad Sci U S A. 1987 Sep.

Abstract

We have isolated a cDNA clone representing the complete coding sequence of a human gene named erg, related to the ets oncogene. Nucleotide sequence analysis of this cDNA (4.6 kilobases long) revealed that this gene encodes a 363-residue protein whose predicted amino acid sequence showed a homology of approximately equal to 40% and approximately equal to 70% to two domains corresponding to the 5' and 3' regions of v-ets oncogene, respectively. A 3.2- to 3.6-kilobase and approximately equal to 5-kilobase transcript of the erg gene, which differ in size from those of the previously described Hu-ets 1 and Hu-ets 2 genes, were observed in different cells. These results suggest that the erg gene is a member of the ets oncogene family.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463-7 - PubMed
    1. Methods Enzymol. 1980;65(1):499-560 - PubMed
    1. Virology. 1981 Sep;113(2):765-8 - PubMed
    1. J Mol Biol. 1982 May 5;157(1):105-32 - PubMed
    1. Cell. 1982 Dec;31(3 Pt 2):643-53 - PubMed

Associated data