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. 2021 Dec 1;34(12):15-20.
doi: 10.1097/01.JAA.0000800232.29507.22.

Understanding resistant hypertension

Alexandra Bachinsky  1 , Erin Leah Jones, Tiffany Thompson, Sondra DePalma, Joyce Nicholas, Eric Schmidt
Affiliations

Understanding resistant hypertension

Alexandra Bachinsky et al. JAAPA. .

Abstract

Resistant hypertension affects about 17% of the US population. However, it is difficult to diagnose because of multiple factors that influence adequate treatment of BP, including patient lifestyle and comorbidities, improper therapeutic regimens, and secondary mechanisms. Possible causes of resistant hypertension include nonmodulator hypertension, which affects patients who have an inappropriate response to elevated sodium through the renin-angiotensin-aldosterone system. Early identification and frequent follow-up can help patients achieve BP goals more rapidly and may reduce morbidity and mortality associated with complications of hypertension, including cerebrovascular accident, cardiovascular disease, and kidney disease.

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References

    1. Whelton PK, Carey RM, Aronow WS, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension . 2018;71(6):1269–1324.
    1. Carey RM, Calhoun DA, Bakris GL, et al. Resistant hypertension: detection, evaluation, and management: a scientific statement from the American Heart Association. Hypertension . 2018;72(5):e53–e90.
    1. Doroszko A, Janus A, Szahidewicz-Krupska E, et al. Resistant hypertension. Adv Clin Exp Med . 2016;25(1):173–183.
    1. Noubiap JJ, Nansseu JR, Nyaga UF, et al. Global prevalence of resistant hypertension: a meta-analysis of data from 3.2 million patients. Heart . 2019;105(2):98–105.
    1. Dudenbostel T, Siddiqui M, Gharpure N, Calhoun DA. Refractory versus resistant hypertension: novel distinctive phenotypes. J Nat Sci . 2017;3(9):e430.

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