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. 2022 Apr;186(4):740-742.
doi: 10.1111/bjd.20893. Epub 2022 Jan 20.

The potential skin-lightening candidate, senolytic drug ABT263, for photoageing pigmentation

Ji Hee Park  1   2 , Jeong Eun Yoon  1   2 , Yul Hee Kim  3 , Yeongeun Kim  2   3 , Tae Jun Park  1   2 , Hee Young Kang  2   3
Affiliations

The potential skin-lightening candidate, senolytic drug ABT263, for photoageing pigmentation

Ji Hee Park et al. Br J Dermatol. 2022 Apr.
No abstract available

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References

    1. Fitsiou E, Pulido T, Campisi J et al. Cellular senescence and the senescence-associated secretory phenotype as drivers of skin photoaging. J Invest Dermatol 2021; 141 (Suppl. 4):1119-26.
    1. Kirkland JL, Tchkonia T, Zhu Y et al. The clinical potential of senolytic drugs. J Am Geriatr Soc 2017; 65:2297-301.
    1. Yoon JE, Kim Y, Kwon S et al. Senescent fibroblasts drive ageing pigmentation: a potential therapeutic target for senile lentigo. Theranostics 2018; 8:4620-32.
    1. Kang HY, Lee JW, Papaccio F et al. Alterations of the pigmentation system in the aging process. Pigment Cell Melanoma Res 2021; 34:800-13.
    1. Kovacs D, Cardinali G, Aspite N et al. Role of fibroblast-derived growth factors in regulating hyperpigmentation of solar lentigo. Br J Dermatol 2010; 163:1020-7.