Mapping GWAS loci to kidney genes and cell types

Affiliations

¹ Division of Nephrology, Department of Medicine, Vagelos College of Physicians & Surgeons, Columbia University, New York, New York, USA.
² Division of Nephrology, Department of Medicine, Vagelos College of Physicians & Surgeons, Columbia University, New York, New York, USA. Electronic address: Kk473@columbia.edu.

Comment

Katherine Xu et al. Kidney Int. 2022 Mar.

. 2022 Mar;101(3):447-450.

doi: 10.1016/j.kint.2021.10.026. Epub 2021 Nov 10.

¹ Division of Nephrology, Department of Medicine, Vagelos College of Physicians & Surgeons, Columbia University, New York, New York, USA.
² Division of Nephrology, Department of Medicine, Vagelos College of Physicians & Surgeons, Columbia University, New York, New York, USA. Electronic address: Kk473@columbia.edu.

No abstract available

Keywords: cell-type specific eQTL; cell-type specific open chromatin; chronic kidney disease; functional genomics; gene expression.

Comment on

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments.
Sheng X, Guan Y, Ma Z, Wu J, Liu H, Qiu C, Vitale S, Miao Z, Seasock MJ, Palmer M, Shin MK, Duffin KL, Pullen SS, Edwards TL, Hellwege JN, Hung AM, Li M, Voight BF, Coffman TM, Brown CD, Susztak K. Sheng X, et al. Nat Genet. 2021 Sep;53(9):1322-1333. doi: 10.1038/s41588-021-00909-9. Epub 2021 Aug 12. Nat Genet. 2021. PMID: 34385711 Free PMC article.