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Case Reports
. 2021:34:101543.
doi: 10.1016/j.rmcr.2021.101543. Epub 2021 Nov 6.

COVID-19 associated respiratory failure complicating a pericardial effusion in a patient with sideroblastic anemia

Edouard Sayad  1 , Mohamad Hammoud  1 , Dima Khreis  2 , Maher El Shami  1 , Maroun Matar  1 , Roula Farah  1
Affiliations
Free PMC article
Case Reports

COVID-19 associated respiratory failure complicating a pericardial effusion in a patient with sideroblastic anemia

Edouard Sayad et al. Respir Med Case Rep. 2021.
Free PMC article

Abstract

Background: COVID-19 disease has been associated with several cardiovascular complications that rarely occur in the acute phase of the disease.

Case report: A 13-year-old pediatric patient with congenital sideroblastic anemia associated with YARS2 mutation presenting with COVID-19 infection and worsening pericardial effusion followed by a respiratory failure refractory to supplemental oxygen therapy leading to cardiac arrest.

Discussion: This case highlights the rapid deterioration that can occur in children with serious hematologic disorders in the context of COVID-19 especially when complicated with pericardial effusion.

Conclusion: The importance of pericardiocentesis early in order to allow better ventilation in any significant pericardial effusion case associated with COVID-19 infection and the need for prompt care escalation to centers where ECMO is available.

Keywords: COVID-19; ECMO; Pericardial effusion; Sideroblastic anemia; YARS2.

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Conflict of interest statement

All authors declare that they have no conflict of interest.

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