. 2022 Jan;42(1):23-29.

doi: 10.1007/s00296-021-05046-4. Epub 2021 Nov 15.

COVID-19 vaccination in autoimmune disease (COVAD) survey protocol

Parikshit Sen¹, Latika Gupta^{2

3}, James B Lilleker^{4

5}, Vishwesh Aggarwal⁶, Sinan Kardes⁷, Marcin Milchert⁸, Tamer Gheita⁹, Babur Salim¹⁰, Tsvetelina Velikova¹¹, Abraham Edgar Gracia-Ramos¹², Ioannis Parodis^{13

14}, Albert Selva O'Callaghan¹⁵, Elena Nikiphorou^{16

17}, Ai Lyn Tan^{18

19}, Lorenzo Cavagna²⁰, Miguel A Saavedra²¹, Samuel Katsuyuki Shinjo²², Nelly Ziade^{23

24}, Johannes Knitza²⁵, Masataka Kuwana²⁶, Giovanni Cagnotto^{27

28}, Arvind Nune²⁹, Oliver Distler³⁰, Hector Chinoy^{31

32

33}, Vikas Aggarwal³⁴, Rohit Aggarwal³⁵; COVAD Study Group

Collaborators, Affiliations

Collaborators

COVAD Study Group:
Bhupen Barman, Yogesh Preet Singh, Rajiv Ranjan, Avinash Jain, Sapan C Pandya, A N Malaviya, Rakesh Kumar Pilania, Aman Sharma, M Manesh Manoj, Vikas Gupta, Chengappa G Kavadichanda, Pradeepta Sekhar Patro, Sajal Ajmani, Sanat Phatak, Rudra Prosad Goswami, Abhra Chandra Chowdhury, Ashish Jacob Mathew, Padnamabha Shenoy, Ajay Asranna, Keerthi Talari Bommakanti, Anuj Shukla, R Naveen, Döndü Üsküdar Cansu, John D Pauling, Chris Wincup, Tulika Chatterjee, Minchul Kim, Margherita Giannini, Nicoletta Del Papa, Gianluca Sambataro, Atzeni Fabiola, Marcello Govoni, Simone Parisi, Elena Bartoloni Bocci, Gian Domenico Sebastiani, Enrico Fusaro, Marco Sebastiani, Luca Quartuccio, Franco Franceschini, Pier Paolo Sainaghi, Giovanni Orsolini, Rossella De Angelis, Maria Giovanna Danielli, Lisa S Traboco, Suryo Anggoro Kusumo Wibowo, Jorge Rojas Serrano, Ignacio García-De La Torre, Erick Adrian Zamora Tehozol, Jesús Loarce-Martos, Sergio Prieto-González, Albert Gil-Vila, Raquel Aranega, Ran Nakashima, Shinji Sato, Naoki Kimura, Yuko Kaneko, Stylianos Tomaras, Margarita Aleksandrovna Gromova, Or Aharonov

Affiliations

¹ Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, Delhi, 110002, India.
² Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Rae Bareilley Road, Lucknow, 226014, India. drlatikagupta@gmail.com.
³ Department of Rheumatology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, WV10 0QP, UK. drlatikagupta@gmail.com.
⁴ Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.
⁵ Manchester Centre for Clinical Neurosciences, Salford Royal NHS Foundation Trust, Salford, UK.
⁶ Mahatma Gandhi Mission Medical College, Navi Mumbai, Maharashtra, India.
⁷ Department of Medical Ecology and Hydroclimatology, Istanbul Faculty of Medicine, Istanbul University, Capa-Fatih, Istanbul, 34093, Turkey.
⁸ Department of Rheumatology, Internal Medicine, Geriatrics and Clinical Immunology, Pomeranian Medical University, ul Unii Lubelskiej 1, 71-252, Szczecin, Poland.
⁹ Rheumatology Department, Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt.
¹⁰ Rheumatology Department, Fauji Foundation Hospital, Rawalpindi, Pakistan.
¹¹ Department of Clinical Immunology, Medical Faculty, University Hospital "Lozenetz", Sofia University St. Kliment Ohridski, 1 Kozyak Str., Sofia, 1407, Bulgaria.
¹² Department of Internal Medicine, General Hospital, National Medical Center "La Raza", Instituto Mexicano del Seguro Social, Av. Jacaranda S/N, Col. La Raza, Del. Azcapotzalco, C.P. 02990, Mexico City, Mexico.
¹³ Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
¹⁴ Department of Rheumatology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
¹⁵ Internal Medicine Department, Vall D'hebron General Hospital, Universitat Autonoma de Barcelona, 08035, Barcelona, Spain.
¹⁶ Centre for Rheumatic Diseases, King's College London, London, UK.
¹⁷ Rheumatology Department, King's College Hospital, London, UK.
¹⁸ NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK.
¹⁹ Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.
²⁰ Rheumatology Unit, Dipartimento di Medicine Interna e Terapia Medica, Università Degli Studi di Pavia, Pavia, Lombardy, Italy.
²¹ Departamento de Reumatología Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro Médico Nacional La Raza, IMSS, Mexico City, Mexico.
²² Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, SP, Brazil.
²³ Rheumatology Department, Saint-Joseph University, Beirut, Lebanon.
²⁴ Rheumatology Department, Hôtel-Dieu de France Hospital, Beirut, Lebanon.
²⁵ Medizinische Klinik 3 - Rheumatologie und Immunologie, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Ulmenweg 18, 91054, Erlangen, Germany.
²⁶ Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8602, Japan.
²⁷ Rheumatology, Department of Clinical Sciences, Lund University, Malmö, Sweden.
²⁸ Department of Rheumatology, Skåne University Hospital, Lund, Sweden.
²⁹ Southport and Ormskirk Hospital NHS Trust, Southport, PR8 6PN, UK.
³⁰ Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
³¹ Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester, UK.
³² National Institute for Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, The University of Manchester, Manchester, UK.
³³ Department of Rheumatology, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, UK.
³⁴ Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Rae Bareilley Road, Lucknow, 226014, India.
³⁵ Division of Rheumatology and Clinical Immunology, Department of Medicine, UPMC Arthritis and Autoimmunity Center, School of Medicine, University of Pittsburgh, 3601 Fifth Ave., Suite 2B, Pittsburgh, PA, 15213, USA. aggarwalr@upmc.edu.

PMID: 34779868
PMCID: PMC8591970
DOI: 10.1007/s00296-021-05046-4

COVID-19 vaccination in autoimmune disease (COVAD) survey protocol

Parikshit Sen et al. Rheumatol Int. 2022 Jan.

. 2022 Jan;42(1):23-29.

doi: 10.1007/s00296-021-05046-4. Epub 2021 Nov 15.

Authors

Collaborators

COVAD Study Group:
Bhupen Barman, Yogesh Preet Singh, Rajiv Ranjan, Avinash Jain, Sapan C Pandya, A N Malaviya, Rakesh Kumar Pilania, Aman Sharma, M Manesh Manoj, Vikas Gupta, Chengappa G Kavadichanda, Pradeepta Sekhar Patro, Sajal Ajmani, Sanat Phatak, Rudra Prosad Goswami, Abhra Chandra Chowdhury, Ashish Jacob Mathew, Padnamabha Shenoy, Ajay Asranna, Keerthi Talari Bommakanti, Anuj Shukla, R Naveen, Döndü Üsküdar Cansu, John D Pauling, Chris Wincup, Tulika Chatterjee, Minchul Kim, Margherita Giannini, Nicoletta Del Papa, Gianluca Sambataro, Atzeni Fabiola, Marcello Govoni, Simone Parisi, Elena Bartoloni Bocci, Gian Domenico Sebastiani, Enrico Fusaro, Marco Sebastiani, Luca Quartuccio, Franco Franceschini, Pier Paolo Sainaghi, Giovanni Orsolini, Rossella De Angelis, Maria Giovanna Danielli, Lisa S Traboco, Suryo Anggoro Kusumo Wibowo, Jorge Rojas Serrano, Ignacio García-De La Torre, Erick Adrian Zamora Tehozol, Jesús Loarce-Martos, Sergio Prieto-González, Albert Gil-Vila, Raquel Aranega, Ran Nakashima, Shinji Sato, Naoki Kimura, Yuko Kaneko, Stylianos Tomaras, Margarita Aleksandrovna Gromova, Or Aharonov

Affiliations

¹ Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, Delhi, 110002, India.
² Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Rae Bareilley Road, Lucknow, 226014, India. drlatikagupta@gmail.com.
³ Department of Rheumatology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, WV10 0QP, UK. drlatikagupta@gmail.com.
⁴ Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.
⁵ Manchester Centre for Clinical Neurosciences, Salford Royal NHS Foundation Trust, Salford, UK.
⁶ Mahatma Gandhi Mission Medical College, Navi Mumbai, Maharashtra, India.
⁷ Department of Medical Ecology and Hydroclimatology, Istanbul Faculty of Medicine, Istanbul University, Capa-Fatih, Istanbul, 34093, Turkey.
⁸ Department of Rheumatology, Internal Medicine, Geriatrics and Clinical Immunology, Pomeranian Medical University, ul Unii Lubelskiej 1, 71-252, Szczecin, Poland.
⁹ Rheumatology Department, Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt.
¹⁰ Rheumatology Department, Fauji Foundation Hospital, Rawalpindi, Pakistan.
¹¹ Department of Clinical Immunology, Medical Faculty, University Hospital "Lozenetz", Sofia University St. Kliment Ohridski, 1 Kozyak Str., Sofia, 1407, Bulgaria.
¹² Department of Internal Medicine, General Hospital, National Medical Center "La Raza", Instituto Mexicano del Seguro Social, Av. Jacaranda S/N, Col. La Raza, Del. Azcapotzalco, C.P. 02990, Mexico City, Mexico.
¹³ Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
¹⁴ Department of Rheumatology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
¹⁵ Internal Medicine Department, Vall D'hebron General Hospital, Universitat Autonoma de Barcelona, 08035, Barcelona, Spain.
¹⁶ Centre for Rheumatic Diseases, King's College London, London, UK.
¹⁷ Rheumatology Department, King's College Hospital, London, UK.
¹⁸ NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK.
¹⁹ Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.
²⁰ Rheumatology Unit, Dipartimento di Medicine Interna e Terapia Medica, Università Degli Studi di Pavia, Pavia, Lombardy, Italy.
²¹ Departamento de Reumatología Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro Médico Nacional La Raza, IMSS, Mexico City, Mexico.
²² Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, SP, Brazil.
²³ Rheumatology Department, Saint-Joseph University, Beirut, Lebanon.
²⁴ Rheumatology Department, Hôtel-Dieu de France Hospital, Beirut, Lebanon.
²⁵ Medizinische Klinik 3 - Rheumatologie und Immunologie, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Ulmenweg 18, 91054, Erlangen, Germany.
²⁶ Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8602, Japan.
²⁷ Rheumatology, Department of Clinical Sciences, Lund University, Malmö, Sweden.
²⁸ Department of Rheumatology, Skåne University Hospital, Lund, Sweden.
²⁹ Southport and Ormskirk Hospital NHS Trust, Southport, PR8 6PN, UK.
³⁰ Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
³¹ Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester, UK.
³² National Institute for Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, The University of Manchester, Manchester, UK.
³³ Department of Rheumatology, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, UK.
³⁴ Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Rae Bareilley Road, Lucknow, 226014, India.
³⁵ Division of Rheumatology and Clinical Immunology, Department of Medicine, UPMC Arthritis and Autoimmunity Center, School of Medicine, University of Pittsburgh, 3601 Fifth Ave., Suite 2B, Pittsburgh, PA, 15213, USA. aggarwalr@upmc.edu.

PMID: 34779868
PMCID: PMC8591970
DOI: 10.1007/s00296-021-05046-4

Abstract

The coronavirus disease-2019 (COVID-19) pandemic continues to be a cause of unprecedented global morbidity and mortality. Whilst COVID-19 vaccination has emerged as the only tangible solution to reducing poor clinical outcomes, vaccine hesitancy continues to be an obstacle to achieving high levels of vaccine uptake. This represents particular risk to patients with autoimmune diseases, a group already at increased risk of hospitalization and poor clinical outcomes related to COVID-19 infection. Whilst there is a paucity of long-term safety and efficacy data of COVID-19 vaccination in patients with autoimmune diseases, the current evidence strongly suggests that the benefits of vaccination outweigh the risks of adverse effects and disease flares. Herein, we report the protocol of the COVID-19 Vaccination in Autoimmune Diseases (COVAD) study, an ongoing international collaborative study involving 29 countries and over 110 investigators.

Keywords: Autoimmune diseases; COVAD; COVID-19; Survey; Vaccination.

PubMed Disclaimer

Conflict of interest statement

OD has/had consultancy relationship with and/or has received research funding from or has served as a speaker for the following companies in the area of potential treatments for systemic sclerosis and its complications in the last 3 years: Abbvie, Acceleron, Alcimed, Amgen, AnaMar, Arxx, Baecon, Blade, Bayer, Boehringer Ingelheim, ChemomAb, Corbus, CSL Behring, Galapagos, Glenmark, GSK, Horizon (Curzion), Inventiva, iQvia, Kymera, Lupin, Medac, Medscape, Mitsubishi Tanabe, Novartis, Roche, Roivant, Sanofi, Serodapharm, Topadur and UCB. Patent issued “mir-29 for the treatment of systemic sclerosis” (US8247389, EP2331143). The rest of the authors have no COI relevant to this manuscript.

References

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COVID-19 vaccination in autoimmune disease (COVAD) survey protocol

Collaborators

Affiliations

COVID-19 vaccination in autoimmune disease (COVAD) survey protocol

Authors

Collaborators

Affiliations

Abstract

Conflict of interest statement

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