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Review
. 2021 Oct 26;9(30):8953-8966.
doi: 10.12998/wjcc.v9.i30.8953.

Endothelial progenitor cells and coronary artery disease: Current concepts and future research directions

Sen-Tong Xiao  1 , Chun-Yan Kuang  2
Affiliations
Review

Endothelial progenitor cells and coronary artery disease: Current concepts and future research directions

Sen-Tong Xiao et al. World J Clin Cases. .

Abstract

Vascular injury is a frequent pathology in coronary artery disease. To repair the vasculature, scientists have found that endothelial progenitor cells (EPCs) have excellent properties associated with angiogenesis. Over time, research on EPCs has made encouraging progress regardless of pathology or clinical technology. This review focuses on the origins and cell markers of EPCs, and the connection between EPCs and coronary artery disease. In addition, we summarized various studies of EPC-capturing stents and EPC infusion therapy, and aim to learn from past technology to predict the future.

Keywords: Clinical application; Coronary disease; Endothelial progenitor cells; Endothelial progenitor-cell capture stents; Endothelial progenitor-cell infusion.

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Conflict of interest statement

Conflict-of-interest statement: The authors report that they have no conflicting interests.

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