Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Dec;53(1):2165-2177.
doi: 10.1080/07853890.2021.2004322.

Dermatology for the internist: optimal diagnosis and management of atopic dermatitis

Affiliations
Review

Dermatology for the internist: optimal diagnosis and management of atopic dermatitis

Shanthi Narla et al. Ann Med. 2021 Dec.

Abstract

Internists are front-line health care providers that commonly provide the first encounter to patients for dermatological conditions, especially atopic dermatitis (AD). Internists need to be comfortable with managing mild-moderate AD in their practices. Criteria and guidelines established in dermatology literature are available to help the general practitioner diagnose and treat AD. AD is a systemic disease associated with multiple cutaneous and extra-cutaneous comorbidities that warrant screening by internists, especially mental health conditions. Environmental factors may play a role in the development or worsening of AD; however, there is currently no strong evidence to guide specific population- or clinic-based interventions for their avoidance. While food allergies are common in AD patients, the role of food allergens as an exacerbating factor for AD is controversial. Before starting any dietary modifications, careful evaluation should be performed by an allergist. If the patient is not well-controlled despite adequate topical therapies or is experiencing severe/worsening disease, early referral to dermatology is warranted to rule out confounding diagnoses and/or escalation to systemic therapies. Finally, it is important to recognise the racial disparities present in AD and address these when formulating treatment plans.Key messages:Confounding dermatoses, either instead of or in addition to AD, should be considered in treatment-refractory AD, and the appropriate workup may be initiated while awaiting dermatology referral.AD patients have multiple cutaneous and extra-cutaneous comorbidities that warrant screening by internists, especially mental health conditions.

Keywords: Atopic dermatitis; autoimmune conditions; bleach baths; cardiovascular; comorbidities; depression; diagnosis; environmental factors; food allergies; infections; internist; mental health; racial disparities; screening; sleep; treatment.

PubMed Disclaimer

Conflict of interest statement

SN has no conflicts of interest to report. JIS has received honoraria as a consultant, advisory board member or speaker for Abbvie, Afyx, Arena, Asana, BioMX, Bluefin, Bodewell, Boehringer-Ingelheim, Celgene, Dermavant, Dermira, Eli Lilly, Galderma, GlaxoSmithKline, Incyte, Kiniksa, Leo, Luna, Menlo, Novartis, Pfizer, RAPT, Regeneron, Sanofi; institution received grants from Galderma.

Similar articles

Cited by

References

    1. Silverberg JI, Simpson EL.. Associations of childhood eczema severity: a US population-based study. Dermatitis. 2014;25(3):107–114. - PMC - PubMed
    1. Chiesa Fuxench ZC, Block JK, Boguniewicz M, et al. . Atopic dermatitis in America study: a cross-sectional study examining the prevalence and disease burden of atopic dermatitis in the US adult population. J Invest Dermatol. 2019;139(3):583–590. - PubMed
    1. Glazer AM, Rigel DS.. Analysis of trends in geographic distribution of US dermatology workforce density. JAMA Dermatol. 2017;153(5):472–473. - PMC - PubMed
    1. Hua T, Silverberg JI.. Atopic dermatitis in US adults: epidemiology, association with marital status, and atopy. Ann Allergy Asthma Immunol. 2018;121(5):622–624. - PubMed
    1. Sacotte R, Silverberg JI.. Epidemiology of adult atopic dermatitis. Clin Dermatol. 2018;36(5):595–605. - PubMed