Double-blind- evaluation of bromperidol versus haloperidol treatment in chronic psychotic patients

Abstract

Twenty four chronic psychotic patients were assigned at random to bromperidol or haloperidol. The mean dose for bromperidol was 4 to 8 mg in one intake in the morning and for haloperidol 4 mg given twice a day. Regular evaluation was performed by BPRS, global clinical impression, side-effects scale, hematological and biochemical screening. It appears that bromperidol is a potent antipsychotic drug with a duration of 24 h. Compared to haloperidol, it favours social integration by a mild but definite activating property. No major side-effects were observed.