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Review
. 2022 Feb;46(2):273-299.
doi: 10.1002/jpen.2306. Epub 2022 Jan 3.

Parenteral nutrition compatibility and stability: A comprehensive review

Joseph I Boullata  1 , Jay M Mirtallo  2   3 , Gordon S Sacks  4 , Genene Salman  5 , Kathleen Gura  6   7 , Todd Canada  8 , Angela Maguire  9 ; ASPEN Parenteral Nutrition Safety Committee  2
Affiliations
Review

Parenteral nutrition compatibility and stability: A comprehensive review

Joseph I Boullata et al. JPEN J Parenter Enteral Nutr. 2022 Feb.

Abstract

Several guidance documents support best practices across the stages of the parenteral nutrition (PN) use process to optimize patient safety. The critical step of PN order verification and review by the pharmacist requires a contextual assessment of the compatibility and stability implications of the ordered PN prescription. This article will provide working definitions, describe PN component characteristics, and present a wide-ranging representation of compatibility and stability concerns that need to be considered prior to preparing a PN admixture. This paper has been approved by the American Society for Parenteral and Enteral Nutrition (ASPEN) Board of Directors.

Keywords: compatibility; parenteral nutrition; stability.

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References

REFERENCES

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    1. Boullata JI, Gilbert K, Sacks G, et al. American Society for Parenteral and Enteral Nutrition. A.S.P.E.N. Clinical guidelines: parenteral nutrition ordering, order review, compounding, labeling, and dispensing. JPEN J Parenter Enteral Nutr. 2014;38(3):334-377.
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