Equilibrating SSC guidelines with individualized care

Jean-Louis Vincent¹, Mervyn Singer², Sharon Einav³, Rui Moreno⁴, Julia Wendon⁵, Jean-Louis Teboul⁶, Jan Bakker^{7

8

9

10}, Glenn Hernandez¹¹, Djillali Annane¹², Angélique M E de Man¹³, Xavier Monnet¹⁴, V Marco Ranieri¹⁵, Olfa Hamzaoui¹⁶, Jukka Takala¹⁷, Nicole Juffermans^{18

19}, Jean-Daniel Chiche²⁰, Sheila N Myatra²¹, Daniel De Backer²²

Affiliations

¹ Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, 1070, Brussels, Belgium. jlvincent@intensive.org.
² Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, WC1E 6BT, UK.
³ General Intensive Care Unit, Shaare Zedek Medical Centre, and Hebrew University Faculty of Medicine, Jerusalem, Israel.
⁴ Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Faculdade de Ciências Médicas de Lisboa, Nova Médical School, Lisbon, Portugal.
⁵ Department of Critical Care, Liver Sciences, Department of Inflammation Biology, King's College London, London, SE5 9RS, UK.
⁶ Service de Médecine Intensive-Réanimation, Hôpital de Bicêtre, GHU APHP, Inserm UMR S_999, Université Paris-Saclay, 94270, Le Kremlin-Bicêtre, France.
⁷ Division of Pulmonary, Critical Care, and Sleep Medicine, New York University School of Medicine, New York, NY, 10016, USA.
⁸ Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, NY, 10032, USA.
⁹ Department of Intensive Care Adults, Erasmus MC University Medical Center, 3015 GD, Rotterdam, The Netherlands.
¹⁰ Department of Intensive Care, Pontificia Universidad Católica de Chile, Santiago, Chile.
¹¹ Departmento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
¹² School of Medicine Simone Veil, Raymond Poincaré Hospital (APHP), Department of Intensive Care Medicine, FHU SEPSIS, University of Versailles-University Paris Saclay, 92380, Garches, France.
¹³ Department of Intensive Care Medicine, Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam Medical Data Science (AMDS), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, 1081 HV, Amsterdam, The Netherlands.
¹⁴ AP-HP, Service de médecine intensive-réanimation, Hôpital de Bicêtre, DMU CORREVE, Inserm UMR S_999, FHU SEPSIS, Groupe de Recherche Clinique CARMAS, Université Paris-Saclay, 94270, Le Kremlin-Bicêtre, France.
¹⁵ Department of Emergency and Intensive Care Medicine, Policlinico di Sant'Orsola, Alma Mater Studiorum University of Bologna, 40138, Bologna, Italy.
¹⁶ Service de Réanimation Polyvalente, Hôpital Antoine Béclère, AP-HP, Université Paris-Saclay, 92140, Clamart, France.
¹⁷ Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland.
¹⁸ Laboratory of Experimental Intensive Care and Anaesthesiology, Amsterdam University Medical Centre, Location Academic Medical Centre, 1105 AZ, Amsterdam, The Netherlands.
¹⁹ Department of Intensive Care, OLVG Hospital, Amsterdam, The Netherlands.
²⁰ Department of Intensive Care Medicine, Centre Hospitalier Universitaire Vaudois, 1011, Lausanne, Switzerland.
²¹ Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, 400012, Mumbai, India.
²² Department of Intensive Care, CHIREC Hospital, Université Libre de Bruxelles, Brussels, Belgium.

PMID: 34789298
PMCID: PMC8596086
DOI: 10.1186/s13054-021-03813-0

Editorial

Equilibrating SSC guidelines with individualized care

Jean-Louis Vincent et al. Crit Care. 2021.

. 2021 Nov 17;25(1):397.

doi: 10.1186/s13054-021-03813-0.

Authors

Affiliations

¹ Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, 1070, Brussels, Belgium. jlvincent@intensive.org.
² Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, WC1E 6BT, UK.
³ General Intensive Care Unit, Shaare Zedek Medical Centre, and Hebrew University Faculty of Medicine, Jerusalem, Israel.
⁴ Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Faculdade de Ciências Médicas de Lisboa, Nova Médical School, Lisbon, Portugal.
⁵ Department of Critical Care, Liver Sciences, Department of Inflammation Biology, King's College London, London, SE5 9RS, UK.
⁶ Service de Médecine Intensive-Réanimation, Hôpital de Bicêtre, GHU APHP, Inserm UMR S_999, Université Paris-Saclay, 94270, Le Kremlin-Bicêtre, France.
⁷ Division of Pulmonary, Critical Care, and Sleep Medicine, New York University School of Medicine, New York, NY, 10016, USA.
⁸ Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, NY, 10032, USA.
⁹ Department of Intensive Care Adults, Erasmus MC University Medical Center, 3015 GD, Rotterdam, The Netherlands.
¹⁰ Department of Intensive Care, Pontificia Universidad Católica de Chile, Santiago, Chile.
¹¹ Departmento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
¹² School of Medicine Simone Veil, Raymond Poincaré Hospital (APHP), Department of Intensive Care Medicine, FHU SEPSIS, University of Versailles-University Paris Saclay, 92380, Garches, France.
¹³ Department of Intensive Care Medicine, Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Science (ACS), Amsterdam Infection and Immunity Institute (AI&II), Amsterdam Medical Data Science (AMDS), Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, 1081 HV, Amsterdam, The Netherlands.
¹⁴ AP-HP, Service de médecine intensive-réanimation, Hôpital de Bicêtre, DMU CORREVE, Inserm UMR S_999, FHU SEPSIS, Groupe de Recherche Clinique CARMAS, Université Paris-Saclay, 94270, Le Kremlin-Bicêtre, France.
¹⁵ Department of Emergency and Intensive Care Medicine, Policlinico di Sant'Orsola, Alma Mater Studiorum University of Bologna, 40138, Bologna, Italy.
¹⁶ Service de Réanimation Polyvalente, Hôpital Antoine Béclère, AP-HP, Université Paris-Saclay, 92140, Clamart, France.
¹⁷ Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, 3010, Bern, Switzerland.
¹⁸ Laboratory of Experimental Intensive Care and Anaesthesiology, Amsterdam University Medical Centre, Location Academic Medical Centre, 1105 AZ, Amsterdam, The Netherlands.
¹⁹ Department of Intensive Care, OLVG Hospital, Amsterdam, The Netherlands.
²⁰ Department of Intensive Care Medicine, Centre Hospitalier Universitaire Vaudois, 1011, Lausanne, Switzerland.
²¹ Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, 400012, Mumbai, India.
²² Department of Intensive Care, CHIREC Hospital, Université Libre de Bruxelles, Brussels, Belgium.

PMID: 34789298
PMCID: PMC8596086
DOI: 10.1186/s13054-021-03813-0

No abstract available

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Conflict of interest statement

The authors declare that they have no competing interests.

References

1. Vincent JL, Marshall JC. Surviving sepsis: a guide to the guidelines. Crit Care. 2008;12:162. doi: 10.1186/cc6924. - DOI - PMC - PubMed
1. Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021;47:1181–1247. - PMC - PubMed
1. Santacruz CA, Pereira AJ, Celis E, Vincent JL. Which multicenter randomized controlled trials in critical care medicine have shown reduced mortality? A systematic review. Crit Care Med. 2019;47:1680–1691. doi: 10.1097/CCM.0000000000004000. - DOI - PubMed
1. Vincent JL, Sakr Y. Clinical trial design for unmet clinical needs: a spotlight on sepsis. Expert Rev Clin Pharmacol. 2019;12:893–900. doi: 10.1080/17512433.2019.1643235. - DOI - PubMed
1. Deans KJ, Minneci PC, Suffredini AF, Danner RL, Hoffman WD, Ciu X, et al. Randomization in clinical trials of titrated therapies: unintended consequences of using fixed treatment protocols. Crit Care Med. 2007;35:1509–1516. doi: 10.1097/01.CCM.0000266584.40715.A6. - DOI - PubMed

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Equilibrating SSC guidelines with individualized care

Affiliations

Equilibrating SSC guidelines with individualized care

Authors

Affiliations

Conflict of interest statement

References

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources