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Review
. 2021 Nov 1:12:753007.
doi: 10.3389/fphar.2021.753007. eCollection 2021.

Advances in the Extraction, Purification, Structural Characteristics and Biological Activities of Eleutherococcus senticosus Polysaccharides: A Promising Medicinal and Edible Resource With Development Value

Xiaojie Li  1   2 , Cai Chen  1   3 , Aijing Leng  3   4 , Jialin Qu  1   3
Affiliations
Review

Advances in the Extraction, Purification, Structural Characteristics and Biological Activities of Eleutherococcus senticosus Polysaccharides: A Promising Medicinal and Edible Resource With Development Value

Xiaojie Li et al. Front Pharmacol. .

Abstract

In recent years, natural polysaccharides have received growing attention and interest in view of their values in food, medical, cosmetics and other fields. Eleutherococcus senticosus (E. senticosus) is a medicine and food homologous plant that possess anti-tumor, anti-inflammatory, central nervous system and cardiovascular protection, anti-radiation, enhancement of human microcirculation, improvement of physical fatigue effects, mainly based on lignans, flavonoids and coumarin types. E. senticosus polysaccharides (ESPS), act as a kind of polysaccharide extracted and isolated from the root and rhizome of E. senticosus, have been found in many applications of medicine and food for their unique biological activity. Nevertheless, the existing studies are mostly concerned with small molecules of E. senticosus, less attention is paid to polysaccharides. Moreover, the types and structural characterization of ESPS reported in existing literature were also not summarized. In this paper, the research progress of ESPS is reviewed from the aspects of extraction, separation, structural characterization and biological activity, future perspectives from points of efficient extraction, resource utilization and quality control standards were also proposed, which provide reference for the further development and utilization of ESPS.

Keywords: ); Eleutherococcus senticosus polysaccharides (ESPS; bioactivities; extraction; purification; structure.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

GRAPHICAL ABSTRACT
GRAPHICAL ABSTRACT
FIGURE 1
FIGURE 1
Eleutherococcus senticosus. Salad from leaves (A); tea (B); pulp (C); wine (D); tablets (E); cortex (F).
FIGURE 2
FIGURE 2
Schematic diagram of extraction, purification and structural characterization of ESPS.
FIGURE 3
FIGURE 3
Schematic diagram of biological activity mechanism of ESPS.
See this image and copyright information in PMC

References

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