Decoding complex patterns of oncogene amplification

David Pellman^{1

2

3}, Cheng-Zhong Zhang^{4

5}

Affiliations

¹ Howard Hughes Medical Institute, Chevy Chase, MD, USA. David_Pellman@dfci.harvard.edu.
² Blavatnick Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA. David_Pellman@dfci.harvard.edu.
³ Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. David_Pellman@dfci.harvard.edu.
⁴ Blavatnick Institute, Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
⁵ Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA.

Comment

David Pellman et al. Nat Genet. 2021 Dec.

. 2021 Dec;53(12):1626-1627.

doi: 10.1038/s41588-021-00974-0.

David Pellman^{1

2

3}, Cheng-Zhong Zhang^{4

5}

¹ Howard Hughes Medical Institute, Chevy Chase, MD, USA. David_Pellman@dfci.harvard.edu.
² Blavatnick Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA. David_Pellman@dfci.harvard.edu.
³ Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. David_Pellman@dfci.harvard.edu.
⁴ Blavatnick Institute, Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
⁵ Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA.

No abstract available

Comment on

Chromothripsis followed by circular recombination drives oncogene amplification in human cancer.
Rosswog C, Bartenhagen C, Welte A, Kahlert Y, Hemstedt N, Lorenz W, Cartolano M, Ackermann S, Perner S, Vogel W, Altmüller J, Nürnberg P, Hertwig F, Göhring G, Lilienweiss E, Stütz AM, Korbel JO, Thomas RK, Peifer M, Fischer M. Rosswog C, et al. Nat Genet. 2021 Dec;53(12):1673-1685. doi: 10.1038/s41588-021-00951-7. Epub 2021 Nov 15. Nat Genet. 2021. PMID: 34782764