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. 2021 Nov 14;13(11):e19563.
doi: 10.7759/cureus.19563. eCollection 2021 Nov.

The Role of Minimally Invasive Surgery in Gastric Cancer

Nail Omarov  1 , Derya Uymaz  2 , Ibrahim F Azamat  2 , Emre Ozoran  2 , Ibrahim H Ozata  2 , Fatih S Bırıcık  3 , Orhun C Taskin  4 , Emre Balik  5
Affiliations

The Role of Minimally Invasive Surgery in Gastric Cancer

Nail Omarov et al. Cureus. .

Abstract

Objective: This study aims to investigate the efficacy and safety of minimally invasive surgery (MIS) in gastric cancer and to compare MIS versus open gastrectomy (OG) in terms of early mortality and morbidity, long-term oncological outcomes, and recurrence rates.

Methods: A total of 75 patients who underwent MIS or OG for gastric cancer at Koç University School of Medicine between December 2014 and December 2019 were retrospectively analyzed. Postoperative complications and disease-specific survival were compared between surgical approaches.

Results: Of the patients, 44 were treated with MIS and 31 with OG. In the MIS group, 33 patients underwent laparoscopic surgery, and 11 patients underwent robotic gastrectomy. Duration of operation was significantly longer in the MIS group than in the OG group (p<0.0001). The median amount of blood loss was 142.5 (range, 110 to 180) mL in the MIS group and 180.4 (range, 145 to 230) mL in the OG group (p<0.706). The median number of lymph node dissection was 38.9 (range, 15 to 66) and 38.7 (range, 12 to 70) in the MIS and OG groups, respectively (p<0.736). The median length of hospitalization, twelve days in the OG group and nine days in the MIS group. Median follow-up was 19.1 (range, 2 to 61) months in the MIS group and 22.1 (range, 2 to 58) months in the OG group. The median OS and DFS rates were 56.8 months and 39.6 months in the MIS group, respectively (log-rank; p=0.004) and 31.6 months and 23.1 months in the OG group, respectively (log-rank; p=0.003).

Conclusion: Our study results suggest that, despite its technical challenges, MIS is an effective and safe method in treating gastric cancer with favorable early mortality and morbidity rates and long-term oncological outcomes, and acceptable recurrence rates.

Keywords: gastrectomy; gastric cancer surgery; minimally invasive laparoscopy; oncology; robotic assited surgery.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Study flow chart
Figure 2
Figure 2. The long-term outcomes of the patients
Figure 3
Figure 3. Irrespective of the surgical technique, Kaplan-Meier plot showing DFS
DFS: disease-free survival
Figure 4
Figure 4. Irrespective of the surgical technique, Kaplan-Meier plot showing OS
OS: overall survival
See this image and copyright information in PMC

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