Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Nov 11;15(21):8713-24.
doi: 10.1093/nar/15.21.8713.

A human Y-chromosomal DNA sequence expressed in testicular tissue

J Arnemann  1 , J T Epplen, H J Cooke, U Sauermann, W Engel, J Schmidtke
Affiliations
Free PMC article

A human Y-chromosomal DNA sequence expressed in testicular tissue

J Arnemann et al. Nucleic Acids Res. .
Free PMC article

Abstract

Clone pJA36B (DYS14) was isolated from a human Y chromosome enriched cosmid library. Southern blot analysis revealed a male-specific hybridization pattern. Deletion mapping with patients' DNA localized pJA36B to the median region of Yp, being present in the DNA of nine of fifteen XX-males tested so far and therefore localized in the region neighbouring the TDF-locus. Northern blot analysis showed a transcription signal in poly(A)+ RNA of human testis. Sequence analysis of the genomic DNA sequence revealed an open reading frame of 522 basepairs in the absence of control or signal sequences for the regulation of transcription or polyadenylation. This suggests that only one exon of a translatable sequence is present in clone pJA36B. A computer aided search revealed no significant homologies with known DNA or protein sequences.

PubMed Disclaimer

References

    1. J Mol Biol. 1977 Jun 15;113(1):237-51 - PubMed
    1. Nucleic Acids Res. 1986 Aug 26;14(16):6489-505 - PubMed
    1. Chromosoma. 1980;79(2):137-57 - PubMed
    1. Hum Genet. 1980;55(2):145-75 - PubMed
    1. J Mol Biol. 1980 Oct 25;143(2):161-78 - PubMed

Publication types

Associated data