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Review
. 2022 Feb;40(1):17-32.
doi: 10.1016/j.ncl.2021.08.002.

Acute Treatment of Ischemic Stroke

Stephanie Lyden  1 , Jana Wold  2
Affiliations
Review

Acute Treatment of Ischemic Stroke

Stephanie Lyden et al. Neurol Clin. 2022 Feb.

Abstract

Ischemic stroke affects 2.5% of the population of the United States and is the leading cause of disability. This article outlines the evidence to support intravenous thrombolysis with alteplase and tenecteplase, thrombolysis in the setting of DWI/flair mismatch, endovascular treatment in the 6-hour and 6- to 24-hour window, and the use of telemedicine in acute stroke. Current controversies and ongoing trials within endovascular treatment are also detailed. Case presentations are included to provide clinical context and the application of data to practice.

Keywords: Acute ischemic stroke; Endovascular treatment; Thrombolysis.

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Conflict of interest statement

Disclosure The authors have nothing to disclose.