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. 1987 Dec;41(6):1117-23.

Inheritance of human-erythrocyte Gerbich blood group antigens

M E Reid  1 , C Sullivan, M Taylor, D J Anstee
Affiliations

Inheritance of human-erythrocyte Gerbich blood group antigens

M E Reid et al. Am J Hum Genet. 1987 Dec.

Abstract

The blood group-antigenic determinant Gerbich was first described greater than 25 years ago, but its mode of inheritance has not been established. We performed protein immunoblotting by means of anti-beta sialoglycoprotein (SGP) and anti-gamma SGP reagents. The anti-beta SGP was a monoclonal antibody that reacts with normal beta SGP and with the abnormal beta-related SGPs associated with Gerbich and Yus types of Ge-negative red cells. In the families studied, we have shown that the products of the Ge alleles are inherited in an autosomal codominant manner.

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