A clinical trial in oral surgery of the analgesic efficacy of a suprofen/codeine combination
- PMID: 3479917
- PMCID: PMC2148546
A clinical trial in oral surgery of the analgesic efficacy of a suprofen/codeine combination
Abstract
Suprofen as well as codeine have been shown to be effective analgesics. In this study, a 200-mg suprofen/60-mg codeine dose is scored for analgesic efficacy and safety compared to suprofen (200 mg), codeine (60 mg), and placebo. One hundred sixty-five healthy, adult patients were asked to rate degree of pain experienced over a six-hour period after medication. The combination treatment was found to offer maximum pain relief. Dentists should be aware that flank pain and renal function abnormalities have been reported in postmarketing surveillance.
Similar articles
-
Oral analgesic efficacy of suprofen compared to aspirin, aspirin plus codeine, and placebo in patients with postoperative dental pain.Pharmacology. 1983;27 Suppl 1:31-40. doi: 10.1159/000137897. Pharmacology. 1983. PMID: 6361789 Clinical Trial.
-
The analgesic efficacy of suprofen in periodontal and oral surgical pain.Pharmacotherapy. 1986 Sep-Oct;6(5):267-76. doi: 10.1002/j.1875-9114.1986.tb03487.x. Pharmacotherapy. 1986. PMID: 3540879 Clinical Trial.
-
Evaluation of two opioid-acetaminophen combinations and placebo in postoperative oral surgery pain.Pharmacotherapy. 1994 Mar-Apr;14(2):139-46. Pharmacotherapy. 1994. PMID: 8197031 Clinical Trial.
-
Suprofen: the pharmacology and clinical efficacy of a new non-narcotic peripheral analgesic.Clin Rheum Dis. 1984 Aug;10(2):353-68. Clin Rheum Dis. 1984. PMID: 6439459 Review.
-
Relative efficacy of oral analgesics after third molar extraction.Br Dent J. 2004 Oct 9;197(7):407-11; discussion 397. doi: 10.1038/sj.bdj.4811721. Br Dent J. 2004. PMID: 15475903 Review.
Cited by
-
The efficacy of nonopioid analgesics for postoperative dental pain: a meta-analysis.Anesth Prog. 1997 Fall;44(4):119-26. Anesth Prog. 1997. PMID: 9481955 Free PMC article.
-
Summary of the scientific literature for pain and anxiety control in dentistry journal literature, January 1986-December 1987.Anesth Prog. 1988 Nov-Dec;35(6):247-65. Anesth Prog. 1988. PMID: 12487126 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources