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Comment
. 2022 Jan;19(1):6.
doi: 10.1038/s41569-021-00648-8.

Truncated titin proteins in the pathophysiology of DCM

Karina Huynh  1
Affiliations
Comment

Truncated titin proteins in the pathophysiology of DCM

Karina Huynh. Nat Rev Cardiol. 2022 Jan.
No abstract available

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Comment on

  • Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations.
    Fomin A, Gärtner A, Cyganek L, Tiburcy M, Tuleta I, Wellers L, Folsche L, Hobbach AJ, von Frieling-Salewsky M, Unger A, Hucke A, Koser F, Kassner A, Sielemann K, Streckfuß-Bömeke K, Hasenfuss G, Goedel A, Laugwitz KL, Moretti A, Gummert JF, Dos Remedios CG, Reinecke H, Knöll R, van Heesch S, Hubner N, Zimmermann WH, Milting H, Linke WA. Fomin A, et al. Sci Transl Med. 2021 Nov 3;13(618):eabd3079. doi: 10.1126/scitranslmed.abd3079. Epub 2021 Nov 3. Sci Transl Med. 2021. PMID: 34731013
  • Truncated titin proteins in dilated cardiomyopathy.
    McAfee Q, Chen CY, Yang Y, Caporizzo MA, Morley M, Babu A, Jeong S, Brandimarto J, Bedi KC Jr, Flam E, Cesare J, Cappola TP, Margulies K, Prosser B, Arany Z. McAfee Q, et al. Sci Transl Med. 2021 Nov 3;13(618):eabd7287. doi: 10.1126/scitranslmed.abd7287. Epub 2021 Nov 3. Sci Transl Med. 2021. PMID: 34731015 Free PMC article.

References

Original article
    1. McAfee, Q. et al. Truncated titin proteins in dilated cardiomyopathy. Sci. Transl Med. https://doi.org/10.1126/scitranslmed.abd7287 (2021) - DOI - PubMed
    1. Formin, A. et al. Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations. Sci. Transl Med. https://doi.org/10.1126/scitranslmed.abd3079 (2021) - DOI

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