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Comment
. 2022 Jan;22(1):1.
doi: 10.1038/s41577-021-00663-3.

Vitamin D shuts down T cell-mediated inflammation

Kirsty Minton  1
Affiliations
Comment

Vitamin D shuts down T cell-mediated inflammation

Kirsty Minton. Nat Rev Immunol. 2022 Jan.

Abstract

This study links the complement-mediated retraction of T helper 1 cell responses to vitamin D receptor signalling, an autoregulatory loop that might be impaired in patients with COVID-19.

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Figures

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Comment on

  • Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells.
    Chauss D, Freiwald T, McGregor R, Yan B, Wang L, Nova-Lamperti E, Kumar D, Zhang Z, Teague H, West EE, Vannella KM, Ramos-Benitez MJ, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz DM, Portilla D, Chertow DS, John S, Lavender P, Kemper C, Lombardi G, Mehta NN, Cooper N, Lionakis MS, Laurence A, Kazemian M, Afzali B. Chauss D, et al. Nat Immunol. 2022 Jan;23(1):62-74. doi: 10.1038/s41590-021-01080-3. Epub 2021 Nov 11. Nat Immunol. 2022. PMID: 34764490 Free PMC article.

References

    1. Chauss D, et al. Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells. Nat. Immunol. 2021 doi: 10.1038/s41590-021-01080-3. - DOI - PMC - PubMed