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Affiliations

¹ Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
² Graduate School of Public Health University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
³ Washington University School of Medicine and John Cochran VA Medical Center, St. Louis, Missouri, USA.
⁴ Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA.
⁵ Division of Gastrointestinal and Liver Diseases, Keck Medicine of University of Southern California, Los Angeles, California, USA.
⁶ Toronto Center for Liver Disease, University of Toronto, Toronto, Ontario, Canada.
⁷ Department of Medicine, Division of Gastroenterology and Hepatology, University of California San Francisco, San Francisco, California, USA.
⁸ Hepatology and Liver Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
⁹ Meredith Mosle Chair in Liver Disease, UT Southwestern Medical Center, Dallas, Texas, USA.
¹⁰ Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
¹¹ Head of Infectious Disease Research, Abbott Diagnostics, Abbott Park, Illinois, USA.
¹² Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University, Richmond, Virginia, USA.

Free article

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Marc G Ghany et al. Hepatology. 2022 Mar.

Free article

. 2022 Mar;75(3):761-763.

doi: 10.1002/hep.32251. Epub 2021 Dec 21.

¹ Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
² Graduate School of Public Health University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
³ Washington University School of Medicine and John Cochran VA Medical Center, St. Louis, Missouri, USA.
⁴ Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA.
⁵ Division of Gastrointestinal and Liver Diseases, Keck Medicine of University of Southern California, Los Angeles, California, USA.
⁶ Toronto Center for Liver Disease, University of Toronto, Toronto, Ontario, Canada.
⁷ Department of Medicine, Division of Gastroenterology and Hepatology, University of California San Francisco, San Francisco, California, USA.
⁸ Hepatology and Liver Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
⁹ Meredith Mosle Chair in Liver Disease, UT Southwestern Medical Center, Dallas, Texas, USA.
¹⁰ Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
¹¹ Head of Infectious Disease Research, Abbott Diagnostics, Abbott Park, Illinois, USA.
¹² Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University, Richmond, Virginia, USA.

No abstract available

Comment on

Comparison of HBV RNA and Hepatitis B Core Related Antigen With Conventional HBV Markers Among Untreated Adults With Chronic Hepatitis B in North America.
Ghany MG, King WC, Lisker-Melman M, Lok ASF, Terrault N, Janssen HLA, Khalili M, Chung RT, Lee WM, Lau DTY, Cloherty GA, Sterling RK. Ghany MG, et al. Hepatology. 2021 Nov;74(5):2395-2409. doi: 10.1002/hep.32018. Epub 2021 Sep 9. Hepatology. 2021. PMID: 34133774 Free PMC article. Clinical Trial.
Letter to the editor: New kid in the playground: HBcrAg and risk of HCC.
Wu JW, Tseng TC, Kao JH. Wu JW, et al. Hepatology. 2022 Mar;75(3):760-761. doi: 10.1002/hep.32250. Epub 2022 Jan 9. Hepatology. 2022. PMID: 34800036 No abstract available.

1. Maasoumy B, Wiegand SB, Jaroszewicz J, Bremer B, Lehmann P, Deterding K, et al. Hepatitis B core-related antigen (HBcrAg) levels in the natural history of hepatitis B virus infection in a large European cohort predominantly infected with genotypes A and D. Clin Microbiol Infect. 2015;21:e601-10.
1. Seto W-K, Wong D K-H, Fung J, Huang F-Y, Liu K S-H, Lai C-L, et al. Linearized hepatitis B surface antigen and hepatitis B core-related antigen in the natural history of chronic hepatitis B. Clin Microbiol Infect. 2014;20:1173-80.
1. Tada T, Kumada T, Toyoda H, Kiriyama S, Tanikawa M, Hisanaga Y, et al. HBcrAg predicts hepatocellular carcinoma development: an analysis using time-dependent receiver operating characteristics. J Hepatol. 2016;65:48-56.
1. Tseng T-C, Liu C-J, Hsu C-Y, Hong C-M, Su T-H, Yang W-T, et al. High level of hepatitis B core-related antigen associated with increased risk of hepatocellular carcinoma in patients with chronic HBV infection of intermediate viral load. Gastroenterology. 2019;157:1518-29.e1513.