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. 2022 Feb:96:1-4.
doi: 10.1016/j.ejim.2021.11.002. Epub 2021 Nov 12.

Learning in times of stress: Lessons from COVID-19 that will last throughout this century

Paula Jiménez-Fonseca  1 , Ramón Salazar  2 , Vicent Valentí  3 , Alberto Carmona-Bayonas  4 , Giancarlo Agnelli  5
Affiliations

Learning in times of stress: Lessons from COVID-19 that will last throughout this century

Paula Jiménez-Fonseca et al. Eur J Intern Med. 2022 Feb.

Abstract

Systems tend toward inertia until an external pressure pushes them toward change; thus, a situation of crisis such as the COVID-19 pandemic represents an opportunity for technological innovation. The prevailing need for treatments and vaccines has impelled innovation in the world of randomized clinical trials (RCT), resorting to ideas that had been floating around for a while. Is this merely a circumstantial phenomenon or are new methods here to stay?

Keywords: Bayesian inference; REMAP trials; Response adaptive randomization.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
Pathways of biomedical research.
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