Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Nov 20;24(11):796-803.
doi: 10.3779/j.issn.1009-3419.2021.101.41.

[Advances on Collection and Analysis of Volatile Organic Compounds in the Diagnosis of Lung Cancer]

[Article in Chinese]
Ling Guo  1 , Hong Wu  1 , Qiang Li  1 , Chuan Xu  1 , Yuyang Liu  2
Affiliations

[Advances on Collection and Analysis of Volatile Organic Compounds in the Diagnosis of Lung Cancer]

[Article in Chinese]
Ling Guo et al. Zhongguo Fei Ai Za Zhi. .

Abstract
in English, Chinese

Lung cancer is a leading cause of cancer-related morbidity and mortality globally, which is the biggest menace to the health and life of the population. Screening and early detection of lung cancer are effective in reducing its mortality, and the measurement of volatile organic compounds (VOCs) has become a promising clinical means for early detection, course detection and prognosis management of lung cancer, with advantages of rapid speed, non-invasiveness and convenience. Now, a variety of VOCs collection ways and analysis methods have emerged at home and abroad. This report summarized three aspects, including VOCs collection, multiple methods of analysis and progress in the diagnosis and treatment of lung cancer. At last, we discussed the limitations and prospects of VOCs analysis. .

【中文题目：VOCs采集与分析技术在肺癌诊疗中的 研究进展】 【中文摘要：肺癌是全球范围内发病率和死亡率最高，对人群健康和生命威胁最大的恶性肿瘤之一。筛查与早诊早治是降低人群肺癌死亡率的有效措施。挥发性有机化合物 （volatile organic compounds, VOCs）检测以快捷性、无创性、采样方便成为一种具有广泛前景的检测手段，可用于肺癌的早期发现，病程检测及预后管理。目前国内外涌现出了多种VOCs采集设备及分析技术，本综述主要从VOCs采集技术、分析技术以及在肺癌诊疗中的应用研究进展三方面探讨VOCs研究目前所存在的问题及研究前景。 】 【中文关键词：肺肿瘤；挥发性有机化合物；采集与分析；早期诊断】.

Keywords: Collection and analysis; Early diagnosis; Lung neoplasms; Volatile organic compounds.

PubMed Disclaimer

Figures

图 1
图 1
VOCs来源 Sources of VOCs. VOCs: volatile organic compounds.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–249. doi: 10.3322/caac.21660. - DOI - PubMed
    1. Guerrera F, Errico L, Evangelista A, et al. Exploring stage I non-small-cell lung cancer: development of a prognostic model predicting 5-year survival after surgical resection. Eur J Cardiothorac Surg. 2015;47(6):1037–1043. doi: 10.1093/ejcts/ezu410. - DOI - PubMed
    1. He J, Li N, Chen WQ, et al. China guideline for the screening and early detection of lung cancer (2021, Beijing) Zhonghua Zhong Liu Za Zhi. 2021;43(3):243–268. - PubMed
    2. 赫 捷, 李 霓, 陈 万青, et al. 中国肺癌筛查与早诊早治指南(2021, 北京) 中华肿瘤杂志. 2021;43(3):243–268. doi: 10.3760/cma.j.cn112152-20210119-00060. - DOI - PubMed
    1. Aberle DR, Adams AM, Berg CD, et al. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011;365(5):395–409. doi: 10.1056/NEJMoa1102873. - DOI - PMC - PubMed
    1. Rampinelli C, De Marco P, Origgi D, et al. Exposure to low dose computed tomography for lung cancer screening and risk of cancer: secondary analysis of trial data and risk-benefit analysis. BMJ. 2017;356:j347. doi: 10.1136/bmj.j347. - DOI - PMC - PubMed

Substances