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. 2022 Jan 11;94(1):26-40.
doi: 10.1021/acs.analchem.1c03856. Epub 2021 Nov 22.

Point-of-Care for Evaluating Antimicrobial Resistance through the Adoption of Functional Materials

Sima Singh  1 , Arshid Numan  2 , Stefano Cinti  3   4
Affiliations

Point-of-Care for Evaluating Antimicrobial Resistance through the Adoption of Functional Materials

Sima Singh et al. Anal Chem. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing financial interest.

Figures

Figure 1
Figure 1
Difference between the conventional test procedure vs POCT. Adapted under the terms and conditions of the CC-BY license from Miesler, T.; Wimschneider, C.; Brem, A.; Meinel, L. ACS Biomater. Sci. Eng.2020, 6 (5), 2709–2725 (ref (14)).
Figure 2
Figure 2
Schematic illustration of AMR diagnostic landscape. (a) Description of the routine laboratory diagnostics, (b and c) sites for POC tests and a hierarchical feature for an ideal POC test/device. Adapted under the terms and conditions of the CC-BY license from Dave, V. P.; Ngo, T. A.; Pernestig, A. K.; Tilevik, D.; Kant, K.; Nguyen, T.; Wolff, A.; Bang, D. D. Lab Invest.2019, 99, 452–469 (ref (34)).
Figure 3
Figure 3
Schematic presentation of the role of noble MNPs in numerous biosensors. Adapted under the terms and conditions of the CC-BY license from Malekzad, H.; Sahandi Zangabad, P.; Mirshekari, H.; Karimi, M.; Hamblin, M. R. Noble Metal Nanoparticles in Biosensors: Recent Studies and Applications. Nanotechnol Rev.2017, 6 (3), 301–329 (ref (44)).
Figure 4
Figure 4
Application of lanthanide nanoparticles in sensing. Reproduced from Kumar, B.; Malhotra, K.; Fuku, R.; Van Houten, J.; Qu, G. Y.; Piunno, P. A. E.; Krull, U. J. TrAC–Trends Anal. Chem.2021, 139, 116256 (ref (76)). Copyright 2021, with permission from Elsevier.
Figure 5
Figure 5
Assemblies of dendrimers on electrode surfaces: (A) molecularly organized dendrimer monolayer, (B) monolayer of metal nanoparticle-decorated dendrimers, (C) dendrimer layered on the nanomaterial-modified surface, (D) dendrimer layered on the polymer-coated surface and layer-by-layer assemblies of (E) dendrimer/dendrimer, (F) dendrimer/protein, (G) dendrimer/nanoparticles, and (H) dendrimer/polymer bilayers. Adapted under the terms and conditions of the CC-BY license from Sánchez, A.; Villalonga, A.;Martínez-García, G.; Parrado, C.; Villalonga, R. Dendrimers as Soft Nanomaterials for Electrochemical Immunosensors. Nanomaterials2019, 9 (12), 1745 (ref (103)).
Figure 6
Figure 6
Colorimetric detection of E. coli bacteria. (a) The antimicrobial peptide-based colorimetric bioassay for detecting E. coli. Reproduced from Qiao, Z.; Lei, C.; Fu, Y.; Li, Y. An Antimicrobial Peptide-Based Colorimetric Bioassay for Rapid and Sensitive Detection of E. coli O157:H7. RSC Adv.2017, 7, 15769 (ref (144)). Copyright 2017, with permission of The Royal Society of Chemistry. (b) SERS based detection of E. coli. Zhou, S.; Lu, C.; Li, Y.; Xue, L.; Zhao, C.; Tian, G.; Bao, Y.; Tang, L.; Lin, J.; Zheng, J. ACS Sensors2020, 5 (2), 588–596 (ref (147)). Copyright 2020 American Chemical Society.
Figure 7
Figure 7
Electrochemical biosensors for pathogen detection: components and measurement formats. Reproduced from Cesewski, E.; Johnson, B. N. Electrochemical Biosensors for Pathogen Detection. Biosens Bioelectron.2020, 159, 112214 (ref (163)). Copyright 2020, with permission from Elsevier.
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