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Case Reports
. 2021 Nov;12(11):433-437.
doi: 10.14740/jmc3773. Epub 2021 Nov 5.

Primary Cardiac Lymphoma: A Case Report

Firas Ajam  1 , Priyanka Batchu  1 , Kyle Wiseman  2 , Dhairya Gor  2 , Elisabeth Mason  2 , Abbas Alshami  2 , Steven Douedi  2 , Aditya Mehra  1 , Ravneet Bajwa  3 , Michael Levitt  3 , David Greenberg  3 , Muhammad Raza  1
Affiliations
Case Reports

Primary Cardiac Lymphoma: A Case Report

Firas Ajam et al. J Med Cases. 2021 Nov.

Abstract

Cardiac lymphoma is a rare neoplasm involving heart, pericardium or both, usually seen in immunocompromised patients. We report a 61-year-old male presenting with worsening shortness of breath and 20-pound weight loss. Investigations showed right-sided tumor with interatrial septal wall perforation and left atrial expansion. The diagnosis was confirmed with mediastinal mass biopsy. After receiving the appropriate treatment, there was a steady improvement clinically and on the transesophageal echocardiography.

Keywords: Arrhythmias; Cardiac lymphoma; Cardiac tumors; Chemotherapy.

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Conflict of interest statement

The authors declare that there is no conflict of interest regarding the publication of this paper.

Figures

Figure 1
Figure 1
Atrial flutter with 4:1 block.
Figure 2
Figure 2
(a) Interatrial septal wall thickening. (b) Tricuspid valve mass. (c) Interatrial septal wall perforation and tumor expansion to left atrium.
Figure 3
Figure 3
CT scan chest: right-sided pleural effusion, anterior mediastinal mass. CT: computed tomography.
Figure 4
Figure 4
(a) Follow-up TEE shows regression of tricuspid valve mass and the interatrial septal wall thickness. (b) Regression of the interatrial septal wall tumor thickness. TEE: transesophageal echocardiogram.
See this image and copyright information in PMC

References

    1. Dellas C, Chapuy B, Schweyer S, Hasenfuss G, Hunlich M. A rare cause of sudden cardiac arrest: primary cardiac lymphoma. Clin Res Cardiol. 2009;98(8):509–511. doi: 10.1007/s00392-009-0034-0. - DOI - PMC - PubMed
    1. Chen H, Qian S, Shi P, Liu L, Yang F. A presentation, treatment, and survival analysis of primary cardiac lymphoma cases reported from 2009 to 2019. Int J Hematol. 2020;112(1):65–73. doi: 10.1007/s12185-020-02881-2. - DOI - PubMed
    1. Chen KW, Chang JH, Yeh SP, Lu CR. Primary cardiac B-cell lymphoma with atrioventricular block and paroxysmal ventricular tachycardia. J Cardiothorac Surg. 2012;7:70. doi: 10.1186/1749-8090-7-70. - DOI - PMC - PubMed
    1. Petrich A, Cho SI, Billett H. Primary cardiac lymphoma: an analysis of presentation, treatment, and outcome patterns. Cancer. 2011;117(3):581–589. doi: 10.1002/cncr.25444. - DOI - PubMed
    1. Jonavicius K, Salcius K, Meskauskas R, Valeviciene N, Tarutis V, Sirvydis V. Primary cardiac lymphoma: two cases and a review of literature. J Cardiothorac Surg. 2015;10:138. doi: 10.1186/s13019-015-0348-0. - DOI - PMC - PubMed

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