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Case Reports
. 2021 Nov 15;11(6):830-831.
doi: 10.1080/20009666.2021.1978153. eCollection 2021.

Acute neuroborreliosis presenting with severe hyponatremia: a case report

Affiliations
Case Reports

Acute neuroborreliosis presenting with severe hyponatremia: a case report

Ismaïl Ould-Nana et al. J Community Hosp Intern Med Perspect. .

Abstract

A 79-year-old Caucasian woman was admitted to the hospital with a 1-week history of general deterioration, describing malaise, abdominal pain, vomiting and diarrhea. Concomitantly, she presented with urinary retention. Laboratory tests revealed severe hyponatremia secondary to the syndrome of inappropriate antidiuretic hormone secretion (SIADH). Patient reported a tick bite 1 month earlier, followed by erythema migrans. The diagnosis of Lyme disease was immediately suspected and confirmed by positive IgM and IgG serology. Symptoms and electrolyte disturbances completely resolved with a 2-week course of doxycycline. This case highlights the need to consider osis as a cause of hyponatremia and SIADH in an endemic region.

Keywords: Lyme; doxycycline; hyponatremia.

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

References

    1. Saeed BO, Beaumont D, Handley GH, et al. Severe hyponatraemia: investigation and management in a district general hospital. J Clin Pathol. 2002. Dec;55(12):893–896. - PMC - PubMed
    1. Vantyghem MC, Balavoine AS, Wémeau JL, et al. Hyponatremia and antidiuresis syndrome. Ann Endocrinol (Paris). 2011. Dec;72(6):500–512. - PubMed
    1. Coyle PK, Schutzer SE.. Neurologic aspects of Lyme disease. Med Clin North Am. 2002. Mar;86(2):261–284. - PubMed
    1. Koedel U, Fingerle V, Pfister HW. Lyme neuroborreliosis-epidemiology, diagnosis and management. Nat Rev Neurol. 2015. Aug;11(8):446–456. - PubMed
    1. Shamim EA, Shamim SA, Liss G, et al. Constipation heralding neuroborreliosis: an atypical tale of 2 patients. Arch Neurol. 2005. Apr;62(4):671–673. - PubMed

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