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Case Reports
. 2021 Nov 2:26:e01327.
doi: 10.1016/j.idcr.2021.e01327. eCollection 2021.

Invasive Aspergillus flavus sinusitis in an immunocompetent patient using intranasal cocaine

Lauren Bougioukas  1 , Brendan Campbell  2 , Kyle Crooker  2 , Jason A Freed  3 , Jonathan Wilcock  2 , Devika Singh  1   2 , Andrew J Hale  1   2
Affiliations
Case Reports

Invasive Aspergillus flavus sinusitis in an immunocompetent patient using intranasal cocaine

Lauren Bougioukas et al. IDCases. .

Abstract

Invasive fungal sinusitis is a rare and potentially fatal infection that tends to occur in immunocompromised hosts. Presented is the case of a 33-year-old immunocompetent male with several months of recurrent facial and nasal pain refractory to several antibacterial courses before a diagnosis of invasive Aspergillus sinusitis was made. The patient's symptoms and infection were successfully treated with a combination of surgical debridement and voriconazole. The authors review the epidemiology, risk factors, diagnosis, and treatment of invasive fungal sinusitis due to Aspergillus.

Keywords: Aspergillosis; Aspergillus flavus; Intranasal cocaine; Invasive fungal sinusitis; Maxillary tooth extraction.

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Conflict of interest statement

None of the authors report any conflicts of interest.

Figures

Fig. 1
Fig. 1
Hematoxylin and eosin stain (400x) of sinus tissue demonstrating invasive fungal hyphae with acute angle branching and septations, consistent with Aspergillus species.
See this image and copyright information in PMC

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