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. 1987 Dec;95(6):449-55.
doi: 10.1111/j.1600-0722.1987.tb01959.x.

Malignant transformation in oral leukoplakia

P O Lind  1
Affiliations

Malignant transformation in oral leukoplakia

P O Lind. Scand J Dent Res. 1987 Dec.

Abstract

A retrospective study on the incidence of malignant transformation in oral leukoplakia was performed covering the period from 1970 to 1980. Carcinoma developed in 11 of the 157 patients, and this 7% incidence increased to 8.9% when the same patients were followed prospectively for 6 more years. Dysplasia was found in biopsies from 51 patients (31.8%), and was significantly more frequent in women than men (P less than 0.05). Dysplasia grade and cancer development were related to updated clinical and etiological parameters.

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